Discovery and design of radiopharmaceuticals by in silico methods

M Salahinejad, DA Winkler… - Current …, 2022 - ingentaconnect.com
There has been impressive growth in the use of radiopharmaceuticals for therapy, selective
toxic payload delivery, and noninvasive diagnostic imaging of disease. The increasing …

Enhancement of the thermal and physicochemical properties of styrene butadiene rubber composite foam using nanoparticle fillers and electron beam radiation

HM Eyssa, HM El Refay, MH Sanad - Radiochimica Acta, 2022 - degruyter.com
This study investigates the physicochemical and thermal properties of styrene–butadiene
rubber (SBR) nanocomposite foam. Nano-calcium carbonate (CaCO3) was prepared from …

Radioiodination and biological evaluation of candesartan as a tracer for cardiovascular disorder detection

MH Sanad, KM Sallam, FA Marzook… - Journal of Labelled …, 2016 - Wiley Online Library
The goal of the study aims to evaluate newly radioiodinated candesartan (CAN) as a
potential cardiovascular tracer. CAN was labeled using 125I with chloramine‐T (Ch‐T) and …

Radioiodinated esomeprazole as a model for peptic ulcer localization

MH Sanad, HM Eyssa, NM Gomaa, FA Marzook… - Radiochimica …, 2021 - degruyter.com
This work focuses on tracking stomach ulcer localized in mice. High labeling yield and
radiochemical purity were achieved for the formation of a [125I] esomeprazole radiotracer at …

Radiosynthesis and Biological Evaluation of 99mTc Nitrido-Levetiracetam as a Brain Imaging Agent

MH Sanad, HM Eyssa, FA Marzook, AB Farag… - Radiochemistry, 2021 - Springer
Abstract 99m Tc nitrido-Levetiracetam was prepared using the 99m Tc nitrido core for
labeling. The reaction conditions were optimized to get the highest radiochemical purity …

Comparative Bioevaluation of 99mTc Tricarbonyl and 99mTc-Sn(II) Lansoprazole as a Model for Peptic Ulcer Localization

MH Sanad, HM Eyssa, FA Marzook, AB Farag… - Radiochemistry, 2021 - Springer
Two 99m Tc cores, 99m Tc tricarbonyl and 99m Tc-Sn (II), are compared in labeling of
Lansoprazole (Lans). The optimum conditions of Lansoprazole labeling with 99m Tc in the …

Radioiodinated Procainamide as Radiotracer for Myocardial Perfusion Imaging in Mice

MH Sanad, HM Eyssa, FA Marzook, AB Farag… - Pharmaceutical …, 2023 - Springer
This work focuses on the synthesis and preliminary biological evaluation of [125I]
iodoprocainamide ([125I] iodoPA) as a potential heart-imaging agent.[125I] iodoPAwas …

Comparative biological evaluation between 99mTc(CO)3 and 99mTc-Sn (II) complexes of novel quinoline derivative: a promising infection radiotracer

MH Sanad, ASA El-Bayoumy, AA Ibrahim - Journal of Radioanalytical and …, 2017 - Springer
Abstract A novel quinoline derivative, 2, 2′-[(5-chloro-8-hydroxyquinoline-7-yl)
methylazanediyl] diacetic acid (CHQMADA) was labeled with 99m Tc using SnCl 2· 2H 2 O …

Synthesis, characterization, and bioevaluation of 99mTc nitrido-oxiracetam as a brain imaging model

MH Sanad, SFA Rizvi, AB Farag - Radiochimica Acta, 2021 - degruyter.com
In this work, the radiotracer [99mTc] nitrido-oxiracetam complex was labeled in the presence
of 99mTc-nitrido as a core. In order to get the highest radiochemical purity, many effective …

Radioiodinated famotidine as a new highly selective radiotracer for peptic ulcer disorder detection, diagnostic nuclear imaging and biodistribution

MH Sanad, DH Salama, FA Marzook - Radiochimica Acta, 2017 - degruyter.com
Famotidine was labeled with iodine-125 to obtain 125I-famotidine (125I-fam) as an agent for
ulcer imaging. The radiochemical yield of 125I-famotidine reached approximately …