Why venous leg ulcers have difficulty healing: overview on pathophysiology, clinical consequences, and treatment

JD Raffetto, D Ligi, R Maniscalco, RA Khalil… - Journal of clinical …, 2020 - mdpi.com
Venous leg ulcers (VLUs) are one of the most common ulcers of the lower extremity. VLU
affects many individuals worldwide, could pose a significant socioeconomic burden to the …

An estimate of the economic burden of venous leg ulcers associated with deep venous disease

R Kolluri, M Lugli, L Villalba, R Varcoe… - Vascular …, 2022 - journals.sagepub.com
Introduction: Venous leg ulcers (VLU) embody the most severe stage of the broad spectrum
of chronic venous disease. Approximately 40% of patients with VLU present with the …

Clinical and economic burden of wound care in the tropics: a 5‐year institutional population health review

ZJ Lo, X Lim, D Eng, J Car, Q Hong… - International wound …, 2020 - Wiley Online Library
The aim of this study is to evaluate the clinical and economic burden of wound care in the
Tropics via a 5‐year institutional population health review. Within our data analysis, wounds …

Transparency, openness, and reproducible research practices are frequently underused in health economic evaluations

F Catalá-López, M Ridao, L Tejedor-Romero… - Journal of Clinical …, 2024 - Elsevier
Objectives To investigate the extent to which articles of economic evaluations of healthcare
interventions indexed in MEDLINE incorporate research practices that promote …

Long-term clinical and cost-effectiveness of early endovenous ablation in venous ulceration: a randomized clinical trial

MS Gohel, J Mora, M Szigeti, DM Epstein… - JAMA …, 2020 - jamanetwork.com
Importance One-year outcomes from the Early Venous Reflux Ablation (EVRA) randomized
trial showed accelerated venous leg ulcer healing and greater ulcer-free time for participants …

A randomised controlled trial of compression therapies for the treatment of venous leg ulcers (VenUS 6): study protocol for a pragmatic, multicentre, parallel-group …

CE Arundel, C Welch, P Saramago, U Adderley… - Trials, 2023 - Springer
Background Venous leg ulcer (s) are common, recurring, open wounds on the lower leg,
resulting from diseased or damaged leg veins impairing blood flow. Wound healing is the …

[HTML][HTML] Early versus deferred endovenous ablation of superficial venous reflux in patients with venous ulceration: the EVRA RCT.

MS Gohel, F Heatley, X Liu, A Bradbury… - Health Technology …, 2019 - ncbi.nlm.nih.gov
BACKGROUND Venous ulceration is a common and costly health-care issue worldwide,
with poor healing rates greatly affecting patient quality of life. Compression bandaging has …

The role of venous intervention for the treatment of patients with venous leg ulceration

L Atkin, A Clothier - British Journal of Nursing, 2023 - magonlinelibrary.com
More than 1 million people are estimated to have lower limb venous ulceration in the UK.
Such wounds are predominantly caused by sustained venous hypertension, as a result of …

Compression therapy for NHS inpatients with leg ulcers: a literature review

Y Lian, I Anderson, L Atkin, M Gohel - Journal of Wound Care, 2023 - magonlinelibrary.com
Objective: Leg ulcers are common, distressing and painful for patients, and are a significant
financial burden to healthcare providers. Compression therapy is the mainstay of treatment …

Endovenous ablation for venous leg ulcers

PL Cai, LH Hitchman, AH Mohamed… - Cochrane Database …, 2023 - cochranelibrary.com
Background Venous leg ulcers (VLUs) are a serious manifestation of chronic venous
disease affecting up to 3% of the adult population. This typically recalcitrant and recurring …