During placentation invasive extravillous trophoblasts (EVTs) migrate into the maternal
uterus and modify its vessels. In particular, remodeling of the spiral arteries by EVTs is …

Natural killer (NK) cells have long been considered to be a homogenous population of
innate lymphocytes with limited phenotypic and functional diversity. However, recent …

BACKGROUND Fertility depends on a receptive state of the endometrium, influenced by
hormonal and anatomical adaptations, as well as the immune system. Local and systemic …

Natural killer cells (NKs) are abundant in the human decidua, regulating trophoblast
invasion and angiogenesis. Several diseases of poor placental development are associated …

Natural killer (NK) cells are present in large populations at the maternal-fetal interface during
early pregnancy. However, the role of NK cells in fetal growth is unclear. Here, we have …

The immune cells that reside at the interface between the placenta and uterus are thought to
play many important roles in pregnancy. Recent work has revealed that the composition and …

Tissues are the new frontier of discoveries in immunology. Cells of the immune system are
an integral part of tissue physiology and immunity. Determining how immune cells inhabit …

Innate lymphoid cells (ILCs) are the most abundant immune cells in the uterine mucosa both
before and during pregnancy. Circumstantial evidence suggests they play important roles in …

Pregnancy presents an immunological conundrum because two genetically different
individuals coexist. The maternal lymphocytes at the uterine maternal-fetal interface that can …

During early pregnancy, decidual innate lymphoid cells (dILCs) interact with surrounding
maternal cells and invading fetal extravillous trophoblasts (EVT). Here, using mass …