Bifunctionalized Betulinic Acid Conjugates with C-3-Monodesmoside and C-28-Triphenylphosphonium Moieties with Increased Cancer Cell Targetability

OV Tsepaeva, TI Salikhova, RA Ishkaeva… - Journal of Natural …, 2023 - ACS Publications
A convenient synthesis is presented for a new class of bioactive bifunctionalized conjugates
of lupane-type triterpenoids with triphenylphosphonium (TPP) and glycopyranosyl targeting …

Inhibition of N-type calcium channels by phenoxyaniline and sulfonamide analogues

AS Bispat, FC Cardoso, MM Hasan, Y Dongol… - RSC Medicinal …, 2024 - pubs.rsc.org
Building on previous investigations, structural modifications to the neuronal calcium ion
channel blocker MONIRO-1 and related compounds were conducted that included …

Regulation of pain neurotransmitters and chondrocytes metabolism mediated by voltage-gated ion channels: A narrative review

X Wang, X Li - Heliyon, 2023 - cell.com
Osteoarthritis (OA) is one of the leading causes of chronic pain and dysfunction. It is
essential to comprehend the nature of pain and cartilage degeneration and its influencing …

Phytochemical Profiling and Antioxidant Activities of the Most Favored Ready-to-Use Thai Curries, Pad-Ka-Proa (Spicy Basil Leaves) and Massaman

S Siripongvutikorn, K Pumethakul, CT Yupanqui… - Foods, 2024 - mdpi.com
Food is one of the factors with the highest impact on human health. Today, attention is paid
not only to food properties such as energy provision and palatability but also to functional …

Ethanolic Extracts of Cissus quadrangularis Linn. (Vitaceae) Attenuate Vincristine‐Induced Peripheral Neuropathy in Rats: An Evidence of the Antioxidant, Calcium …

FYM Olga, M Marius, YN William… - Advances in …, 2024 - Wiley Online Library
Cissus quadrangularis Linn.(C. quadrangularis, Vitaceae) is a plant reported to treat injured
tendons, broken bones, asthma, stomach ache, scurvy, and digestive disorders. The present …

Simultaneous use of venlafaxine and calcium channel blockers on tolerance to morphine: The role of mitochondrial damage and oxidative stress in the brain

A Soleimanii, F Fallah, B Ghorbanzadeh… - Pharmacology …, 2024 - Elsevier
Background One of the reasons for tolerance to morphine is increased oxidative stress and
dysfunction of cell mitochondria in the hippocampus. Venlafaxine and calcium channel …