Understanding glycaemic control and current approaches for screening antidiabetic natural products from evidence-based medicinal plants

C Lankatillake, T Huynh, DA Dias - Plant Methods, 2019 - Springer
Abstract Type 2 Diabetes Mellitus has reached epidemic proportions as a result of over-
nutrition and increasingly sedentary lifestyles. Current therapies, although effective, are not …

Metabolomics in the study of retinal health and disease

I Laíns, M Gantner, S Murinello, JA Lasky-Su… - Progress in retinal and …, 2019 - Elsevier
Metabolomics is the qualitative and quantitative assessment of the metabolites (small
molecules< 1.5 kDa) in body fluids. The metabolites are the downstream of the genetic …

Current approach to the pathogenesis of diabetic cataracts

M Mrugacz, M Pony-Uram, A Bryl, K Zorena - International Journal of …, 2023 - mdpi.com
Cataracts remain the first or second leading cause of blindness in all world regions. In the
diabetic population, cataracts not only have a 3–5 times higher incidence than in the healthy …

Dietary patterns, carbohydrates, and age-related eye diseases

SG Francisco, KM Smith, G Aragonès, EA Whitcomb… - Nutrients, 2020 - mdpi.com
Over a third of older adults in the US experience significant vision loss, which decreases
independence and is a biomarker of decreased health span. As the global aging population …

Recent progress and research trend of anti-cataract pharmacology therapy: a bibliometric analysis and literature review

A Lu, P Duan, J Xie, H Gao, M Chen, Y Gong… - European Journal of …, 2022 - Elsevier
Cataract is the leading cause of blindness worldwide. Cataract phacoemulsification
combined with intraocular lens implantation causes great burden to global healthcare …

Metabolomic profiling of aqueous humor in glaucoma points to taurine and spermine deficiency: findings from the eye-D study

A Buisset, P Gohier, S Leruez, J Muller… - Journal of proteome …, 2019 - ACS Publications
We compared the metabolomic profile of aqueous humor from patients with primary open-
angle glaucoma (POAG; n= 26) with that of a group of age-and sex-matched non-POAG …

Preparation and Taste Characteristics of Kokumi N-Lactoyl Phenylalanine in the Presence of Phenylalanine and Lactate

J Wu, J Gao, J Lin, C Cui, L Li, S He… - Journal of Agricultural …, 2022 - ACS Publications
Nl-Lactoyl phenylalanine (Nl-lactoyl-Phe) has been identified as a taste-active contributor in
many fermented foods. However, its preparation, taste property, and content in foodstuffs are …

Quantitative metabolomic analysis of changes in the lens and aqueous humor under development of age-related nuclear cataract

VV Yanshole, LV Yanshole, OA Snytnikova… - Metabolomics, 2019 - Springer
Introduction Metabolites are essential for the proper functioning of the eye lens, they either
enter the lens from the aqueous humor (AH), or are synthesized in the lens epithelium …

Precise Detection of Cataracts with Specific High‐Risk Factors by Layered Binary Co‐Ionizers Assisted Aqueous Humor Metabolic Analysis

C Yang, A Miao, C Yang, C Huang, H Chen… - Advanced …, 2022 - Wiley Online Library
Diabetes and high myopia as well‐known high‐risk factors can aggravate cataracts, yet
clinical coping strategy remains a bottleneck. Metabolic analysis tends to be powerful for …

A 1H NMR metabolomic approach for the estimation of the time since death using aqueous humour: an animal model

E Locci, M Stocchero, A Noto, A Chighine, L Natali… - Metabolomics, 2019 - Springer
Introduction The estimation of the time since death, or post-mortem interval (PMI), still
remains a main conundrum in forensic science. Several approaches have been so far …