Immune modulation of learning, memory, neural plasticity and neurogenesis

R Yirmiya, I Goshen - Brain, behavior, and immunity, 2011 - Elsevier
Over the past two decades it became evident that the immune system plays a central role in
modulating learning, memory and neural plasticity. Under normal quiescent conditions …

GFAP in health and disease

J Middeldorp, EM Hol - Progress in neurobiology, 2011 - Elsevier
Glial fibrillary acidic protein (GFAP) is the main intermediate filament protein in mature
astrocytes, but also an important component of the cytoskeleton in astrocytes during …

[HTML][HTML] Plasma glial fibrillary acidic protein is elevated in cognitively normal older adults at risk of Alzheimer's disease

P Chatterjee, S Pedrini, E Stoops, K Goozee… - Translational …, 2021 - nature.com
Glial fibrillary acidic protein (GFAP), an astrocytic cytoskeletal protein, can be measured in
blood samples, and has been associated with Alzheimer's disease (AD). However, plasma …

Astrocyte activation and reactive gliosis

M Pekny, M Nilsson - Glia, 2005 - Wiley Online Library
Astrocytes become activated (reactive) in response to many CNS pathologies, such as
stroke, trauma, growth of a tumor, or neurodegenerative disease. The process of astrocyte …

[HTML][HTML] GFAP isoforms in adult mouse brain with a focus on neurogenic astrocytes and reactive astrogliosis in mouse models of Alzheimer disease

W Kamphuis, C Mamber, M Moeton, L Kooijman… - 2012 - journals.plos.org
Glial fibrillary acidic protein (GFAP) is the main astrocytic intermediate filament (IF). GFAP
splice isoforms show differential expression patterns in the human brain. GFAPδ is …

Astrocytes in cerebral ischemic injury: morphological and general considerations

KS Panickar, MD Norenberg - Glia, 2005 - Wiley Online Library
Asrocytic responses constitute one of the earliest and most prominent changes in the CNS
following ischemic injury. Astrocytes are known to carry out critical functions such as …

Loss of keratin 6 (K6) proteins reveals a function for intermediate filaments during wound repair

P Wong, PA Coulombe - The Journal of cell biology, 2003 - rupress.org
The ability to heal wounds is vital to all organisms. In mammalian tissues, alterations in
intermediate filament (IF) gene expression represent an early reaction of cells surviving …

The involvement of astrocytes in early‐life adversity induced programming of the brain

MR Abbink, ALF van Deijk, VM Heine, MH Verheijen… - Glia, 2019 - Wiley Online Library
Early‐life adversity (ELA) in the form of stress, inflammation, or malnutrition, can increase the
risk of developing psychopathology or cognitive problems in adulthood. The neurobiological …

Profiling of dynamically changed gene expression in dorsal root ganglia post peripheral nerve injury and a critical role of injury-induced glial fibrillary acetic protein in …

D Kim, KW Figueroa, KW Li, A Boroujerdi, T Yolo… - Pain, 2009 - journals.lww.com
To explore cellular changes in sensory neurons after nerve injury and to identify potential
target genes contributing to different stages of neuropathic pain development, we used …

[HTML][HTML] Early glial responses after acute elevated intraocular pressure in rats

TT Lam, JMK Kwong, MOM Tso - Investigative ophthalmology & …, 2003 - tvst.arvojournals.org
purpose. To study the responses of glial cells to a short-term elevation in intraocular
pressure (IOP) in rats. methods. Adult Sprague-Dawley albino rats, 45 to 55 days old, were …