The increasing use of tissue dosimetry estimated using pharmacokinetic models in chemical
risk assessments in various jurisdictions necessitates the development of internationally …

Over the last couple of decades, the awareness of the potential health impacts associated
with early-life exposures has increased. Global regulatory approaches to chemical risk …

EPA's decision to list a carcinogenic substance as a" hazardous waste," subject to stringent
regulation under the Resource Conserva-tion and Recovery Act, depends on the fatality risk …

Background In 1979 approximately 2,000 people were exposed to polychlorinated
biphenyls (PCBs) and polychlorinated dibenzofurans (PCDFs) due to ingestion of …

Many consumer products are manufactured or synthesized from chemicals. However,
consumers may be hesitant to purchase consumer products that are perceived as synthetic …

Two potential hazardous substance problems are urgent to be solved.(1) Urea–
formaldehyde resin waste that may produce various toxic compounds during conventional …

Background Exposure to toxic chemicals in the home is a growing concern. This report
presents an overview of the recruitment, methods for data collection, instruments used to …

As editors of the second edition of Preclinical Drug Development, we are pleased to present
this updated text on the science of safely moving therapeutic candidates into, and through …

There is increased interest in developing non-animal test systems for inhalation exposure
safety assessments. However, defined methodologies are absent for predicting local …

A micellar electrokinetic capillary chromatography (MEKC) method with ultraviolet visible
(UV) detection was used for the determination of 1, 7‐naphthalenediol, 2, 3 …