Properties and applications of flavonoid metal complexes

MM Kasprzak, A Erxleben, J Ochocki - Rsc Advances, 2015 - pubs.rsc.org
Flavonoids are widely occurring polyphenol compounds of plant origin with multiple
biological and chemical activities. Due to the presence of carbonyl and hydroxyl groups they …

Ruthenium complexes as anticancer agents

I Kostova - Current medicinal chemistry, 2006 - ingentaconnect.com
Cancer is one of the major cases of death in the world. Current treatment of cancer is limited
to surgery, radiotherapy, and the use of cytotoxic agents, despite their well known side …

Dihydromyricetin: A review on identification and quantification methods, biological activities, chemical stability, metabolism and approaches to enhance its …

D Liu, Y Mao, L Ding, XA Zeng - Trends in Food Science & Technology, 2019 - Elsevier
Background Dihydromyricetin (DMY) is an important plant flavonoid, which has received
great attention due to its health-benefiting activities, including antioxidant, antimicrobial, anti …

Inhibitors of lactate dehydrogenase isoforms and their therapeutic potentials

C Granchi, S Bertini, M Macchia… - Current medicinal …, 2010 - ingentaconnect.com
In many different species, lactate dehydrogenase (LDH) constitutes a major checkpoint of
anaerobic glycolysis, by catalyzing the reduction of pyruvate into lactate. This enzyme has …

Structural characterization and cytotoxicity studies of ruthenium (II)–dmso–chloro complexes of chalcone and flavone derivatives

R Prajapati, SK Dubey, R Gaur, RK Koiri, BK Maurya… - Polyhedron, 2010 - Elsevier
A synthetic precursor cis-[RuIICl2 (dmso) 4] is complexed separately with 3-(4-
benzyloxyphenyl)-1-(2-hydroxylphenyl)-prop-2-en-1-one (L1H) and 2-(4-benzyloxyphenyl) …

Metal Cu (II) and Zn (II) bipyridyls as inhibitors of lactate dehydrogenase

RK Koiri, SK Trigun, SK Dubey, S Singh, L Mishra - Biometals, 2008 - Springer
Metal complex–protein interaction is an evolving concept for determining cellular targets of
metallodrugs. Lacatate dehydrogenase (LDH) is critically implicated in tumor growth and …

Heteroleptic ruthenium bioflavonoid complexes: from synthesis to in vitro biological activity

A Zahirović, E Kahrović, M Cindrić… - Journal of …, 2017 - Taylor & Francis
Heteroleptic ruthenium (II) bioflavonoid complexes of quercetin, morin, chrysin, and 3-
hydroxyflavone were prepared and their interaction with CT DNA and BSA along with …

Regression of Dalton's lymphoma in vivo via decline in lactate dehydrogenase and induction of apoptosis by a ruthenium(II)-complex containing 4-carboxy N …

RK Koiri, SK Trigun, L Mishra, K Pandey, D Dixit… - Investigational New …, 2009 - Springer
A novel ruthenium (II)-complex containing 4-carboxy N-ethylbenzamide (Ru (II)-CNEB) was
found to interact with and inhibit M4-lactate dehydrogenase (M4-LDH), a tumor growth …

Photophysical and density functional studies of the interaction of a flavone derivative with the halides

M Sarkar, A Samanta - The Journal of Physical Chemistry B, 2007 - ACS Publications
The synthesis, photophysical behavior, and anion-sensing ability of a fluorescent molecular
system, N-(3-methoxy-4-oxo-2-phenyl-4 H-chromen-7-yl)-benzamide (1H), designed and …

Proapoptotic activity in vitro of two novel ruthenium (II) complexes with flavanone-based ligands that overcome cisplatin resistance in human bladder carcinoma cells

MM Kasprzak, L Szmigiero, E Zyner… - Journal of inorganic …, 2011 - Elsevier
In this study we examined their proapoptotic activity of cis-dichloridobis (3-imino-2-
methoxyflavanone) ruthenium (II) radical dot3H 2 O (1) and cis-dichloridobis (3-imino-2 …