Synthesis of carbocyclic and heterocyclic β-aminocarboxylic acids

L Kiss, F Fülöp - Chemical Reviews, 2014 - ACS Publications
In consequence of their biological effects, conformationally constrained carbocyclic β-amino
acids have generated great interest among synthetic and medicinal chemists in the past 2 …

The chemistry of 2-aminocycloalkanecarboxylic acids

F Fülöp - Chemical Reviews, 2001 - ACS Publications
Although of less importance than their R-analogues, β-amino acids are also present in
peptides and different heterocycles, and their free forms and derivatives exhibit interesting …

Biocatalysis as a profound tool in the preparation of highly enantiopure β-amino acids

A Liljeblad, LT Kanerva - Tetrahedron, 2006 - Elsevier
1. Introduction....................................................................... 5832 2. Kinetic resolutions.....................
............................................ 5833 2.1. Enzymes acting on C–N bonds …

Lipase-catalyzed enantioselective ring opening of unactivated alicyclic-fused β-lactams in an organic solvent

E Forró, F Fülöp - Organic letters, 2003 - ACS Publications
A highly efficient and very simple method was developed for the synthesis of enantiopure β-
amino acids (eg cispentacin) and β-lactams through the enzyme-catalyzed enantioselective …

[PDF][PDF] Enantioselective Synthesis of β-amino acids: A Review

M Ashfaq, R Tabassum, MM Ahmad, NA Hassan… - Med. Chem, 2015 - researchgate.net
Enantioselective Synthesis of β-amino acids: A Review Page 1 Medicinal chemistry Ashfaq et
al. Med chem 2015, 5:7 http://dx.doi.org/10.4172/2161-0444.1000278 Review Article Open …

Synthesis of New β‐Amino Acid Scaffolds by Means of Ring‐Rearrangement Metathesis

A Semghouli, AM Remete, L Kiss - ChemistrySelect, 2022 - Wiley Online Library
The synthesis of some novel functionalized azaheterocyclic β‐amino esters with multiple
chiral centers via a stereocontrolled synthetic route has been carried out using some …

Advanced procedure for the enzymatic ring opening of unsaturated alicyclic β-lactams

E Forró, F Fülöp - Tetrahedron: Asymmetry, 2004 - Elsevier
Enantiopure β-amino acids 1a–4a and β-lactams 1b–4b were prepared simultaneously
through the lipolase-catalysed enantioselective ring opening of unsaturated racemic β …

Total synthesis of crispine A enantiomers through a Burkholderia cepacia lipase-catalysed kinetic resolution

E Forró, L Schönstein, F Fülöp - Tetrahedron: Asymmetry, 2011 - Elsevier
Both enantiomers of the antitumour-active alkaloid crispine A (ee= 95%) were synthesised
through the Burkholderia cepacia lipase-catalysed acylation of the primary hydroxy group of …

[PDF][PDF] Direct and indirect enzymatic methods for the preparation of enantiopure cyclic β-amino acids and derivatives from β-lactams

E Forró, F Fulop - Mini-Reviews in Organic Chemistry, 2004 - academia.edu
Direct enzymatic methods for the preparation of enantiopure cyclic β-amino acids (eg.
cispentacin) and β-lactams through the enzyme-catalyzed enantioselective ring opening of β …

Synthesis of enantiopure 1, 4-ethyl-and 1, 4-ethylene-bridged cispentacin by lipase-catalyzed enantioselective ring opening of β-lactams

E Forró, F Fülöp - Tetrahedron: Asymmetry, 2004 - Elsevier
1, 4-Ethyl-and 1, 4-ethylene-bridged cispentacin enantiomers, and, were prepared through
the lipase-catalyzed enantioselective ring opening of racemic exo-3-azatricyclo [4.2. 1.02. 5] …