Transfusion-transmitted infections (TTI) have been greatly reduced in numbers due to the
strict donor selection and screening procedures, ie the availability of technologies to test …

Standard platelet concentrates (PCs) stored at 22° C have a limited shelf life of 5 days.
Because of the storage temperature, bacterial contamination of PCs can result in life …

Pathogen inactivation (PI) of platelet concentrates (PCs) reduces the proliferation/replication
of a large range of bacteria, viruses, and parasites as well as residual leucocytes. Pathogen …

Plasma membrane-derived microvesicles or microparticles (MPs) are sub-cellular vesicles
released upon shear stress, cell activation, injury or apoptosis. They represent factors of the …

In blood banks, platelets are stored until 7 days after a pathogen reduction technology (PRT)
treatment, Mirasol®(vitamin B 2 plus UVB light) in the present case. The storage time under …

BACKGROUND To increase blood safety, various procedures are currently implemented,
including donor selection, optimized donor arm disinfection, and diversion. In addition …

Pathogen inactivation (PI) for platelet concentrates (PC) is a fairly recent development in
transfusion medicine that is intended to decrease infectious disease transmission from the …

Transfusions of platelets are an important cornerstone of medicine; however, recipients may
be subject to risk of adverse events associated with the potential transmission of pathogens …

Platelet concentrates (PCs) represent a blood transfusion product with a major concern for
safety as their storage temperature (20–24° C) allows bacterial growth, and their maximum …

Blood banks use pathogen inactivation (PI) technologies to increase the safety of platelet
concentrates (PCs). The characteristics of PI-treated PCs slightly differ from those of …