Survival improves when cancer is detected early. However,~ 50% of cancers are at an
advanced stage when diagnosed. Early detection of cancer or precancerous change allows …

Commonly, circulating tumor cells (CTCs) are described as source of metastasis in cancer
patients. However, in this process cancer cells of the primary tumor site need to survive the …

Multicellular aggregates of circulating tumor cells (CTC clusters) are potent initiators of
distant organ metastasis. However, it is currently assumed that CTC clusters are too large to …

Circulating tumor cells (CTCs) carry a wealth of information on primary and metastatic
tumors critical for precise cancer detection, monitoring, and treatment. Numerous …

Early detection of metastasis can be aided by circulating tumor cells (CTC), which also show
potential to predict early relapse. Because of the limited CTC numbers in peripheral blood in …

We are in the midst of a technological revolution that is providing new insights into human
biology and cancer. In this era of big data, we are amassing large amounts of information …

Imaging reveals complex structures and dynamic interactive processes, located deep inside
the body, that are otherwise difficult to decipher. Numerous imaging modalities harness …

Owing to improvements in our understanding of the biological principles of tumour initiation
and progression, a wide variety of novel targeted therapies have been developed …

Lung cancer affects over 1. 8 million people worldwide and is the leading cause of cancer
related mortality globally. Currently, diagnosis of lung cancer involves a combination of …

(1) Background: Circulating tumor cell (CTC) clusters are emerging as clinically significant
harbingers of metastases in solid organ cancers. Prior to engaging these CTC clusters in …