Membrane technology is playing a crucial role in cutting-edge innovations in the biomedical
field. One such innovation is the surface engineering of a membrane for enhanced longevity …

Mechanosensing, or how cells sense and respond to the physical environment, is crucial for
many aspects of biological function, ranging from cell movement during development to …

Cellular response to the topography of their environment, known as contact guidance, is a
crucial aspect to many biological processes yet remains poorly understood. A prevailing …

Regulated cell shape change requires the induction of cortical cytoskeletal domains. Often,
local changes to plasma membrane (PM) topography are involved. Centrosomes organize …

T cell receptor (TCR) clustering and formation of an immune synapse are crucial for TCR
signaling. However, limited information is available about these dynamic assemblies and …

Membraneless organelles (MLO) regulate diverse biological processes in a
spatiotemporally controlled manner spanning from inside to outside of the cells. The plasma …

We investigate how the geometry of elongate mineral particles (EMPs) in contact with cells
influences esotaxis, a recently discovered mechanism of texture sensing. Esotaxis is based …

Natural killer (NK) cells patrol tissue to mediate lysis of virally infected and tumorigenic cells.
Human NK cells are typically identified by their expression of neural cell adhesion molecule …

Nanotopographic surfaces are a powerful tool for studying and controlling cell behavior.
However, the fabrication of nanotopographic master patterns using conventional …

This study investigates the oxygen (O2) consumption of single cells during changes in their
migration direction. This is the first integration of nanotopographies with an O2 biosensor in …