The clinical syndromes comprising urinary tract infection (UTI) continue to exert significant
impact on millions of patients worldwide, most of whom are otherwise healthy women …

The influence of microorganisms growing as sessile communities in a large number of
human infections has been extensively studied and recognized for 30–40 years, therefore …

Escherichia coli is a remarkable and diverse organism. This normally harmless commensal
needs only to acquire a combination of mobile genetic elements to become a highly adapted …

Every mammal on the planet is colonized with E. coli (1), as well as cold‐blooded animals
(eg, fish) at an appropriately warm temperature (2). We estimate there are 1021 E. coli cells …

Urinary tract infections (UTIs) are one of the most common bacterial infections affecting
humans, and uropathogenic Escherichia coli (UPEC) is the etiological agent in 75% to 95 …

Bladder infections affect millions of people yearly, and recurrent symptomatic infections
(cystitis) are very common. The rapid increase in infections caused by multidrug-resistant …

It is interesting to speculate that the evolutionary drive for microbes to develop pathogenic
characteristics was to access the nutrient resources that animals provided. Animal …

Urinary tract infections (UTI) are one of the most common bacterial infections, with roughly
eleven‐million cases reported in the US each year that cost an estimated $5 billion annually …

Bacterial virulence relies on a delicate balance of signals interchanged between the
invading microbe and the host. This communication has been extensively perceived as a …

Chronic infections are an increasing problem due to the aging population and the increase
in antibiotic resistant organisms. Therefore, understanding the host-pathogen interactions …