Skeletal muscle constitutes the largest insulin‐sensitive tissue in the body and is the primary
site for insulin‐stimulated glucose utilization. Skeletal muscle resistance to insulin is …

Recent trials have suggested that inhibitors of the renin–angiotensin system (RAS), such as
angiotensin-converting enzyme (ACE) inhibitors and angiotensin II receptor blockers …

The close relationship between diabetes and hypertension has been recognized for
decades. New information indicates that resistance to insulin action on glucose uptake in …

Effects of oral administration of the angiotensin II receptor antagonist (selective AT1-
subtype) irbesartan on glucose tolerance and insulin action on skeletal-muscle glucose …

OBJECTIVE--To compare the effects of metoprolol and atenolol on carbohydrate and lipid
metabolism and on insulin response to an intravenous glucose load. DESIGN--Randomised …

Nephropathy in type 1 diabetes: A manifestation of insulin resistance and multiple genetic
susceptibilities? Further evidence from the Pittsburgh Epidemiology of Diabetes …

Obesity is a worldwide disease that is accompanied by several metabolic abnormalities
such as hypertension, hyperglycemia and dyslipidemia. The accelerated adipose tissue …

The incidence of end-stage renal failure in patients with type II diabetes has dramatically
increased in recent years, both in the United States and, with some delay, in some European …

Summary Angiotensin II (Ang II), acting on the AT1 and AT2 receptors in mammalian cells, is
the vasoactive component of the renin‐angiotensin system (RAS). Several components of …

The aim of this study was to determine whether insulin sensitivity measured by the
euglycaemic insulin clamp technique is lower in patients with primary hypertension than in …