Sickle cell anaemia (SCA) stands as a hereditary blood disorder characterized by mutated
haemoglobin, causing red blood cells to adopt a sickle shape, leading to complications like …

Studies performed in the last decades have highlighted the need to better understand the
contribution of the endothelium, vascular function, oxidative stress, inflammation …

Early transcranial Doppler (TCD) screening of the Créteil sickle cell anemia (SCA)-newborn
cohort, and rapid initiation of transfusion programs, resulted in successful prevention of overt …

Sickle cell disease (SCD) is a hypercoagulable state. Patients exhibit increased platelet
activation, high plasma levels of markers of thrombin generation, depletion of natural …

Although pulmonary hypertension, leg ulcers, priapism, stroke and glomerulopathy in sickle
cell anaemia (SCA) result from the adverse effects of chronic haemolysis on vascular …

It is well-established that patients with sickle cell disease (SCD) are at substantial risk of
neurological complications, including overt and silent stroke, microstructural injury, and …

Stroke is increasingly recognized as a significant cause of morbidity and mortality in
children, and as a financial burden for families and society. Recent studies have identified …

Objectives. The prevalence of stroke among children with sickle cell disease (SCD) in sub-
Saharan Africa was systematically reviewed. Methods. Comprehensive searches of …

Hematological diseases, due to their complex nature and diverse manifestations, pose
significant diagnostic challenges in healthcare. The pressing need for early and accurate …

Sickle cell disease (SCD) is the most common inherited disease in the world. Red blood cell
sickling, blood cell-endothelium adhesion, blood rheology abnormalities, intravascular …