New Delhi metallo-β-lactamase (NDM) is a metallo-β-lactamase able to hydrolyze almost all
β-lactams. Twenty-four NDM variants have been identified in> 60 species of 11 bacterial …

Klebsiella oxytoca is actually a complex of nine species—Klebsiella grimontii, Klebsiella
huaxiensis, Klebsiella michiganensis, K. oxytoca, Klebsiella pasteurii, Klebsiella …

Conjugation drives the horizontal transfer of adaptive traits across prokaryotes. One-fourth of
the plasmids encode the functions necessary to conjugate autonomously, the others being …

Carbapenem‐resistant Enterobacteriaceae (CRE) have been listed by the WHO as high‐
priority pathogens owing to their high association with mortalities and morbidities …

Antimicrobial resistance is a normal evolutionary process for microorganisms. Antibiotics
exerted accelerated selective pressure that hasten bacterial resistance through mutation …

Background The literature on the epidemiology, mortality and treatment of pandrug-resistant
(PDR) Gram-negative bacteria (GNB) is scarce, scattered and controversial. Objectives To …

For people living in developed countries life span is growing at a faster pace than ever. One
of the main reasons for such success is attributable to the introduction and extensive use in …

The spread of carbapenem-and polymyxin-resistant Enterobacteriaceae poses a significant
threat to public health, challenging clinicians worldwide with limited therapeutic options. This …

We aimed to provide updated epidemiologic data on carbapenem-resistant Klebsiella
pneumoniae in Portugal by characterizing all isolates (N= 46) recovered during 2013–2018 …

Virulence plasmids of hypervirulent Klebsiella pneumoniae (hvKp) have the potential to
transfer to drug-resistant strains or integrate with other plasmids, facilitating the genome …