[HTML][HTML] Raman spectroscopy in pharmaceutical product design

A Paudel, D Raijada, J Rantanen - Advanced drug delivery reviews, 2015 - Elsevier
Almost 100 years after the discovery of the Raman scattering phenomenon, related
analytical techniques have emerged as important tools in biomedical sciences. Raman …

[HTML][HTML] Advances in coamorphous drug delivery systems

Q Shi, SM Moinuddin, T Cai - Acta pharmaceutica sinica B, 2019 - Elsevier
In recent years, the coamorphous drug delivery system has been established as a promising
formulation approach for delivering poorly water-soluble drugs. The coamorphous solid is a …

Recent advances in low-frequency Raman spectroscopy for pharmaceutical applications

K Bērziņš, SJ Fraser-Miller, KC Gordon - International Journal of …, 2021 - Elsevier
Low-frequency Raman (LFR) spectroscopy probes vibrational modes related to long-range
order (ie, crystallinity) that can provide unique information on the solid-state/structural …

Terahertz time-domain and low-frequency Raman spectroscopy of organic materials

EPJ Parrott, JA Zeitler - Applied spectroscopy, 2015 - journals.sagepub.com
With the ongoing proliferation of terahertz time-domain instrumentation from semiconductor
physics into applied spectroscopy over the past decade, measurements at terahertz …

Polymorphism and solvatomorphism 2010

HG Brittain - Journal of pharmaceutical sciences, 2012 - Elsevier
Papers and patents that deal with polymorphism (crystal systems for which a substance can
exist in structures defined by different unit cells and where each of the forms has the same …

Raman imaging of drug delivery systems

GPS Smith, CM McGoverin, SJ Fraser… - Advanced drug delivery …, 2015 - Elsevier
This review article includes an introduction to the principals of Raman spectroscopy, an
outline of the experimental systems used for Raman imaging and the associated important …

Polymorph characterization of active pharmaceutical ingredients (APIs) using low-frequency Raman spectroscopy

PJ Larkin, M Dabros, B Sarsfield, E Chan… - Applied …, 2014 - journals.sagepub.com
Polymorph detection, identification, and quantitation in crystalline materials are of great
importance to the pharmaceutical industry. Vibrational spectroscopic techniques used for …

Boson peak dynamics of glassy glucose studied by integrated terahertz-band spectroscopy

M Kabeya, T Mori, Y Fujii, A Koreeda, BW Lee, JH Ko… - Physical review B, 2016 - APS
We performed terahertz time-domain spectroscopy, low-frequency Raman scattering, and
Brillouin light scattering on vitreous glucose to investigate the boson peak (BP) dynamics. In …

The contribution of Raman spectroscopy to the analysis of phase transformations in pharmaceutical compounds

A Hédoux, Y Guinet, M Descamps - International journal of pharmaceutics, 2011 - Elsevier
We show in this paper the contribution of the whole Raman spectrum including the phonon
spectrum, to detect, identify and characterize polymorphic forms of molecular compounds …

Recent developments in the Raman and infrared investigations of amorphous pharmaceuticals and protein formulations: A review

A Hédoux - Advanced drug delivery reviews, 2016 - Elsevier
The success rate for drug discovery and the development of innovative therapeutic
strategies are intimately related to the physical properties of the solid-state condensed …