The field of stereotactic neurosurgery developed more than 70 years ago to address a
therapy gap for patients with severe psychiatric disorders. In the decades since, it has …

Even though obsessive compulsive disorder (OCD) is one of the ten most disabling
diseases according to the WHO, only 30–40% of patients suffering from OCD seek …

Recent advances in surgical neuromodulation have enabled chronic and continuous
intracranial monitoring during everyday life. We used this opportunity to identify neural …

Background Deep brain stimulation (DBS) is a promising treatment option for treatment-
refractory obsessive-compulsive disorder (OCD). Several stimulation targets have been …

A renewed interest in the use of psychedelics for treating obsessive compulsive disorder
(OCD) has emerged in the last 20 years. But pre-clinical and clinical evidence remain …

Objective. Despite advances in the treatment of psychiatric diseases, currently available
therapies do not provide sufficient and durable relief for as many as 30–40% of patients …

Background Obsessive-compulsive disorder (OCD) is a debilitating illness with substantial
morbidity. Although pharmacological and behavioral evidence–based treatments have …

Background: Deep brain stimulation (DBS) is a highly efficient, evidence-based therapy to
alleviate symptoms and improve quality of life in movement disorders such as Parkinson's …

OBJECTIVE Deep brain stimulation (DBS) is an effective neurosurgical option for patients
with treatment-resistant obsessive-compulsive disorder (OCD). Despite being more costly …

Deep brain stimulation (DBS) has emerged as an invasive neuromodulation technique for
the treatment of several neurological disorders, but the mechanisms underlying its effects …