Effect of NKG2D ligand expression on host immune responses

M Champsaur, LL Lanier - Immunological reviews, 2010 - Wiley Online Library
Natural killer group 2, member D (NKG2D) is an activating receptor present on the surface of
natural killer (NK) cells, some NKT cells, CD8+ cytotoxic T cells, γδ T cells, and under certain …

NKG2D ligands–critical targets for cancer immune escape and therapy

D Schmiedel, O Mandelboim - Frontiers in immunology, 2018 - frontiersin.org
DNA damage, oncogene activation and excessive proliferation, chromatin modulations or
oxidative stress are all important hallmarks of cancer. Interestingly, all of these abnormalities …

Placenta‐derived exosomes and syncytiotrophoblast microparticles and their role in human reproduction: immune modulation for pregnancy success

L Mincheva‐Nilsson, V Baranov - American journal of …, 2014 - Wiley Online Library
The syncytiotrophoblast (STB) of human placenta constitutively produces and secretes
extracellular vesicles of different size, morphology and function that enter the maternal …

MicroRNAs transfer from human macrophages to hepato-carcinoma cells and inhibit proliferation

A Aucher, D Rudnicka, DM Davis - The Journal of Immunology, 2013 - journals.aai.org
Recent research has indicated a new mode of intercellular communication facilitated by the
movement of RNA between cells. There is evidence that RNA can transfer between cells in a …

Cutting edge: Membrane nanotubes connect immune cells

B Önfelt, S Nedvetzki, K Yanagi… - The Journal of …, 2004 - journals.aai.org
We present evidence that nanotubular highways, or membrane nanotubes, facilitate a novel
mechanism for intercellular communication in the immune system. Nanotubes were seen to …

Promiscuity and the single receptor: NKG2D

RA Eagle, J Trowsdale - Nature Reviews Immunology, 2007 - nature.com
NKG2D (natural-killer group 2, member D) is a powerful activating receptor expressed by
natural killer (NK) cells and T cells that regulates immune responses during infection, cancer …

Remodelling of cortical actin where lytic granules dock at natural killer cell immune synapses revealed by super-resolution microscopy

ACN Brown, S Oddos, IM Dobbie, JM Alakoskela… - PLoS …, 2011 - journals.plos.org
Natural Killer (NK) cells are innate immune cells that secrete lytic granules to directly kill
virus-infected or transformed cells across an immune synapse. However, a major gap in …

The role of placental exosomes in reproduction

L Mincheva‐Nilsson, V Baranov - American journal of …, 2010 - Wiley Online Library
Citation Mincheva‐Nilsson L, Baranov V. The Role of Placental Exosomes in Reproduction.
Am J Reprod Immunol 2010 Cell communication comprises cell–cell contact, soluble …

What is the importance of the immunological synapse?

DM Davis, ML Dustin - Trends in immunology, 2004 - cell.com
The immunological synapse (IS) has proved to be a stimulating concept, particularly in
provoking discussion on the similarity of intercellular communication controlling disparate …

NKG2D discriminates diverse ligands through selectively mechano‐regulated ligand conformational changes

J Fan, J Shi, Y Zhang, J Liu, C An, H Zhu, P Wu… - The EMBO …, 2022 - embopress.org
Stimulatory immune receptor NKG2D binds diverse ligands to elicit differential anti‐tumor
and anti‐virus immune responses. Two conflicting degeneracy recognition models based on …