The natural function of many proteins depends on their ability to switch their conformation driven by environmental changes. In this work, we present a small, monomeric β-sheet …
MC Oliveira, RM Cordeiro, A Bogaerts - Archives of Biochemistry and …, 2023 - Elsevier
Intercellular communication plays a crucial role in cancer, as well as other diseases, such as inflammation, tissue degeneration, and neurological disorders. One of the proteins …
N Mandal, N De, P Jana, A Sannigrahi… - ACS Chemical …, 2020 - ACS Publications
The recent outbreak of Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) from Wuhan, China, was caused by a single-stranded RNA virus which has kept the entire …
NE Abo‐Dya, AR Issahaku - ChemistrySelect, 2023 - Wiley Online Library
Abstract Methyltransferase‐like 3 (METTL3) serves as a primary catalytic enzyme within the N6‐methyladenosine (m6 A) methyltransferase system, playing a crucial role in various …
Dynamic conformational and structural changes in proteins and protein complexes play a central and ubiquitous role in the regulation of protein function, yet it is very challenging to …