An extracellular network of molecular chaperones protects a diverse array of proteins that
reside in or pass through extracellular spaces. Proteins in the extracellular milieu face …

The BCL-2-associated athanogene (BAG) family is a multifunctional group of co-chaperones
that are evolutionarily conserved from yeast to mammals. In addition to their common BAG …

Molecular mimicry between foreign and self-antigens has been implicated as a cause of
autoimmune hepatitis in experimental models and cross-reacting antibodies in patients. This …

Benign prostatic hyperplasia (BPH) is one of the most common causes of lower urinary tract
symptoms (LUTS) in men, which is characterized by a noncancerous enlargement of the …

Tau, a microtubule‐associated protein (MAP), is essential to maintaining neuronal stability
and function in the healthy brain. However, aberrant modifications and pathological …

Cancer and other chronic diseases are marked by alterations in the protein quality control
system, affecting the post-translational destiny of various proteins that regulate, structure …

To investigate the involvement of stress induced phosphoprotein 1 (STIP1), heat shock
protein (HSP) 70, and HSP90 in ubiquitination of connexin 43 (Cx43) in rat H9c2 …

Hemolysis in red blood cells followed by hemoglobin degradation results in high hemin
levels in the systemic circulation. Such a level of hemin is disastrous for cells and tissues …

Cancer cells generally overexpress heat shock proteins (Hsps), the major components of
cellular stress response, to overcome and survive the diverse stresses. However, the …

Heat Shock Protein 90 (Hsp90) acts as a crucial molecular chaperone, playing an essential
role in activating numerous signaling proteins. The intricate mechanism of Hsp90 involving …