Abstract Embryonal tumor with Multilayered Rosettes (ETMR) is a relatively rare but typically
deadly type of brain tumor that occurs mostly in infants. Since the discovery of the …

The introduction of molecular methods into the diagnostics of central nervous system (CNS)
tumours and the subsequent deciphering of their molecular heterogeneity has resulted in a …

Background Only few data are available on treatment-associated behavior of distinct rare
CNS embryonal tumor entities previously treated as “CNS-primitive neuroectodermal …

Background Embryonal tumours with multi-layered rosettes (ETMRs) are a newly
recognised, rare paediatric brain tumour with alterations of the C19MC microRNA locus …

The 5th edition of the WHO Classification of Tumours of the Central Nervous System
introduces new entities, and provides updated guidance regarding the diagnostic criteria for …

Embryonal tumors of the central nervous system (CNS) are rare, high-grade neoplasms
predominantly affecting the pediatric population. Well-defined embryonal tumors include …

Background Embryonal tumors with multilayered rosettes (ETMR) are highly aggressive
tumors occurring in early childhood. Published clinical data refer to retrospective …

Objective The classification of brain tumors is a rapidly evolving field that requires extensive
integration of molecular diagnostic findings from an expanding set of platforms and assays …

Purpose We explored the use of intraventricular 131 I-Omburtamab targeting B7-H3 in
patients with ETMR. Methods Patients were enrolled in an IRB approved, phase 1, 3+ 3 …

Introduction ETMRs are highly lethal, pediatric embryonal brain tumors, previously classified
as various histologic diagnoses including supratentorial primitive neuroectodermal tumors …