Serotonin [5-hydroxytryptamine (5-HT)] plays an important role in many organs as a
peripheral hormone. Most of the body's serotonin is circulating in the bloodstream …

Abstract Serotonin (5-HT) has been recognized for decades as an important signalling
molecule in the gut, but it is still revealing its secrets. Novel gastrointestinal functions of 5-HT …

Abstract Serotonin or 5‐hydroxytryptamine (5‐HT) is a neurotransmitter and hormone that
contributes to the regulation of various physiological functions by its actions in the central …

Serotonin was first discovered in the gut, and its conventional actions as an intercellular
signalling molecule in the intrinsic and extrinsic enteric reflexes are well recognized, as are …

Serotonin, also known as 5-hydroxytryptamine (5-HT) is a signaling mediator that regulates
emotion, behavior, and cognition. Previous studies have focused more on the roles of 5-HT …

Platelets are anucleate cell fragments known for their central role in coagulation and
vascular integrity. However, it is becoming increasingly clear that platelets contribute to …

There is now a large body of evidence that platelets are central actors of inflammatory
reactions. Indeed, platelets play a significant role in a variety of inflammatory diseases …

Platelets have long been known for their role in hemostasis. In this, platelet adhesion and
activation leads to the formation of a firm thrombus and thus the sealing of a damaged blood …

The aromatic amino acid L-tryptophan (Trp) is essentially metabolized along the host and
microbial pathways. While much is known about the role played by downstream metabolites …

Group 2 innate lymphoid cells (ILC2s) regulate immunity, inflammation, and tissue
homeostasis. Two distinct subsets of ILC2s have been described: steady-state natural ILC2s …