There has been a significant progress in our understanding of the molecular mechanisms by
which calcium (Ca2+) ions mediate various types of cardiac arrhythmias. A growing list of …

Voltage-gated calcium channels are the primary mediators of depolarization-induced
calcium entry into neurons. There is great diversity of calcium channel subtypes due to …

MICU1 is a calcium (Ca2+)–binding protein that regulates the mitochondrial Ca2+ uniporter
channel complex (mtCU) and mitochondrial Ca2+ uptake. MICU1 knockout mice display …

Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a devastating inherited
disorder characterized by episodic syncope and/or sudden cardiac arrest during exercise or …

Wettability in nanochannels is of great importance for understanding many challenging
problems in interface chemistry and fluid mechanics, and presents versatile applications …

Calcium (Ca2+) is a critical regulator of cardiac myocyte function. Principally, Ca2+ is the
link between the electrical signals that pervade the heart and contraction of the myocytes to …

Activity-dependent gene expression triggered by Ca 2+ entry into neurons is critical for
learning and memory, but whether specific sources of Ca 2+ act distinctly or merely supply …

Calmodulin regulation (calmodulation) of the family of voltage-gated CaV1-2 channels
comprises a prominent prototype for ion channel regulation, remarkable for its powerful …

A rise in cytosolic Ca 2+ concentration is used as a universal signalling mechanism to
control biological processes as diverse as exocytosis, contraction, cell growth and cell …

Rhythmic increases in intracellular Ca2+ concentration underlie the contractile function of
the heart. These heart muscle-wide changes in intracellular Ca2+ are induced and …