Skin is considered as an important route of administration of drugs for both local and
systemic effects. The effectiveness of topical therapy depends on the physicochemical …

Film-forming formulations represent a novel form of sustained release dermatic products.
They are applied to the skin as a liquid or semi-solid preparation. By evaporation of the …

The term “nanoscale” refers to particle size range from~ 1 to 100 nm [1], but for the purpose
of drug delivery, nanoparticles in the range of 50–500 nm are acceptable depending on the …

Novel MOF-based polymer nanocomposite films were successfully prepared using Zr-based
UiO-67 as a metal–organic framework (MOF) and polyurethane (PU) as a polymeric matrix …

The bioavailability of therapeutic agents from eye drops is usually limited due to corneal
barrier functions and effective eye protective mechanisms. Therefore, the current study aims …

The present investigation was taken up to prepare and evaluate drug free polymeric patches
using different polymers and to study the effect of different plasticizers on physicochemical …

Objective: To develop and characterize self-nanoemulsifying drug delivery system
(SNEDDS) of the poorly water-soluble drug, glibenclamide (GBD). Methods: Solubility of …

The global state of antibiotic resistance highlights the necessity for new drugs that can treat
a wide range of microbial infections. Drug repurposing has several advantages, including …

The in vitro dissolution rate constant, dissolution half-life and pharmacokinetic parameters
(Cmax, tmax, AUC (s), t1/2, Kel, and MRT) were evaluated statistically by two-way ANOVA. A …

The glaucoma is an ocular pathology characterized by the increase of intraocular pressure
and possibility of retinal degeneration. The treatment is based on the administration of eye …