[HTML][HTML] Genkwanin: An emerging natural compound with multifaceted pharmacological effects
N El Menyiy, S Aboulaghras, S Bakrim… - Biomedicine & …, 2023 - Elsevier
Plant bioactive molecules could play key preventive and therapeutic roles in chronological
aging and the pathogenesis of many chronic diseases, often accompanied by increased …
aging and the pathogenesis of many chronic diseases, often accompanied by increased …
Phenolic compounds versus SARS-CoV-2: An update on the main findings against COVID-19
VA Tirado-Kulieva, E Hernández-Martínez… - Heliyon, 2022 - cell.com
The COVID-19 pandemic caused by SARS-CoV-2 remains an international concern.
Although there are drugs to fight it, new natural alternatives such as polyphenols are …
Although there are drugs to fight it, new natural alternatives such as polyphenols are …
CuO nanoparticles for green synthesis of significant anti-Helicobacter pylori compounds with in silico studies
WS Shehab, DA Elsayed, AM Abdel Hamid… - Scientific Reports, 2024 - nature.com
Helicobacter pylori (H. pylori) is a universal health intimidation as mentioned by the World
Health Organization. The primary causal agent linked to a number of illnesses, including …
Health Organization. The primary causal agent linked to a number of illnesses, including …
Targeting SARS-CoV-2 macrodomain-1 to restore the innate immune response using in silico screening of medicinal compounds and free energy calculation …
Among the different drug targets of SARS-CoV-2, a multi-domain protein known as NSP3 is
a critical element of the translational and replication machinery. The macrodomain-I, in …
a critical element of the translational and replication machinery. The macrodomain-I, in …
Discovery of natural products to block SARS-CoV-2 S-protein interaction with Neuropilin-1 receptor: A molecular dynamics simulation approach
Abstract Neuropilin-1 (NRP1) is a widely expressed cell surface receptor protein
characterized by its pleiotropic function. Recent reports highlighted NRP1 as an additional …
characterized by its pleiotropic function. Recent reports highlighted NRP1 as an additional …
The regulation of antiviral innate immunity through non-m6A RNA modifications
The post-transcriptional RNA modifications impact the dynamic regulation of gene
expression in diverse biological and physiological processes. Host RNA modifications play …
expression in diverse biological and physiological processes. Host RNA modifications play …
Novel Inhibitors of 2′-O-Methyltransferase of the SARS-CoV-2 Coronavirus
A Sulimov, D Kutov, I Ilin, Y Xiao, S Jiang, V Sulimov - Molecules, 2022 - mdpi.com
The COVID-19 pandemic is still affecting many people worldwide and causing a heavy
burden to global health. To eliminate the disease, SARS-CoV-2, the virus responsible for the …
burden to global health. To eliminate the disease, SARS-CoV-2, the virus responsible for the …
The dolabellane diterpenes as potential inhibitors of the SARS-CoV-2 main protease: molecular insight of the inhibitory mechanism through computational studies
An investigation has been carried out on natural products from dolabellane derivatives to
understand their potential in inhibiting the SARS-CoV-2 main protease (3CLpro) using an in …
understand their potential in inhibiting the SARS-CoV-2 main protease (3CLpro) using an in …
Current status of structure-based drug repurposing against COVID-19 by targeting SARS-CoV-2 proteins
A Hijikata, C Shionyu, S Nakae, M Shionyu… - Biophysics and …, 2021 - jstage.jst.go.jp
More than one and half years have passed, as of August 2021, since the COVID-19 caused
by the novel coronavirus named SARS-CoV-2 emerged in 2019. While the recent success of …
by the novel coronavirus named SARS-CoV-2 emerged in 2019. While the recent success of …
Structure-Based Virtual Screening for Methyltransferase Inhibitors of SARS-CoV-2 nsp14 and nsp16
K Wu, Y Guo, T Xu, W Huang, D Guo, L Cao, J Lei - Molecules, 2024 - mdpi.com
The ongoing COVID-19 pandemic still threatens human health around the world. The
methyltransferases (MTases) of SARS-CoV-2, specifically nsp14 and nsp16, play crucial …
methyltransferases (MTases) of SARS-CoV-2, specifically nsp14 and nsp16, play crucial …