Host–microbiota interactions in inflammatory bowel disease

R Caruso, BC Lo, G Núñez - Nature Reviews Immunology, 2020 - nature.com
The mammalian intestine is colonized by trillions of microorganisms that have co-evolved
with the host in a symbiotic relationship. The presence of large numbers of symbionts near …

[HTML][HTML] Antioxidant and anti-inflammatory roles of tea polyphenols in inflammatory bowel diseases

VL Truong, WS Jeong - Food Science and Human Wellness, 2022 - Elsevier
Polyphenols, including phenolic acids, flavonoids, and procyanidins, are abundant in food
and beverage derived from plants. Tea (Camellia sinensis) is particularly rich in polyphenols …

Dietary cholesterol drives fatty liver-associated liver cancer by modulating gut microbiota and metabolites

X Zhang, OO Coker, ESH Chu, K Fu, HCH Lau… - Gut, 2021 - gut.bmj.com
Objective Non-alcoholic fatty liver disease (NAFLD)-associated hepatocellular carcinoma
(HCC) is an increasing healthcare burden worldwide. We examined the role of dietary …

Akkermansia muciniphila exacerbates food allergy in fibre-deprived mice

A Parrish, M Boudaud, ET Grant, S Willieme… - Nature …, 2023 - nature.com
Alterations in the gut microbiome, including diet-driven changes, are linked to the rising
prevalence of food allergy. However, little is known about how specific gut bacteria trigger …

A high-fat diet increases gut microbiota biodiversity and energy expenditure due to nutrient difference

B Wang, Q Kong, X Li, J Zhao, H Zhang, W Chen… - Nutrients, 2020 - mdpi.com
A high-fat diet (HFD) can easily induce obesity and change the gut microbiota and its
metabolites. However, studies on the effects of high-fat diets on the host have drawn …

A proinflammatory gut microbiota increases systemic inflammation and accelerates atherosclerosis

E Brandsma, NJ Kloosterhuis, M Koster… - Circulation …, 2019 - Am Heart Assoc
Rationale: Several studies have suggested a role for the gut microbiota in inflammation and
atherogenesis. A causal relation relationship between gut microbiota, inflammation, and …

Mucispirillum schaedleri antagonizes Salmonella virulence to protect mice against colitis

S Herp, S Brugiroux, D Garzetti, D Ring, LM Jochum… - Cell host & …, 2019 - cell.com
The microbiota and the gastrointestinal mucus layer play a pivotal role in protection against
non-typhoidal Salmonella enterica serovar Typhimurium (S. Tm) colitis. Here, we analyzed …

The human symbiont Mucispirillum schaedleri: causality in health and disease

S Herp, AC Durai Raj, M Salvado Silva… - Medical microbiology …, 2021 - Springer
Trillions of bacteria inhabit the mammalian gastrointestinal tract. In the majority of hosts,
these symbionts contribute largely to beneficial functions promoting microbe-host …

Dietary betaine prevents obesity through gut microbiota-drived microRNA-378a family

J Du, P Zhang, J Luo, L Shen, S Zhang, H Gu, J He… - Gut …, 2021 - Taylor & Francis
Betaine is a natural compound present in commonly consumed foods and may have a
potential role in the regulation of glucose and lipids metabolism. However, the underlying …

Fiber-deficient diet inhibits colitis through the regulation of the niche and metabolism of a gut pathobiont

P Kuffa, JM Pickard, A Campbell, M Yamashita… - Cell Host & Microbe, 2023 - cell.com
Exclusive enteral nutrition (EEN) with fiber-free diets is an effective steroid-sparing treatment
to induce clinical remission in children with Crohn's disease (CD). However, the mechanism …