Microglia-mediated neuroinflammation and neuroplasticity after stroke
Stroke remains a major cause of long-term disability and mortality worldwide. The immune
system plays an important role in determining the condition of the brain following stroke. As …
system plays an important role in determining the condition of the brain following stroke. As …
Gliotoxicity and glioprotection: the dual role of glial cells
A Quincozes-Santos, CL Santos… - Molecular …, 2021 - Springer
Glial cells (astrocytes, oligodendrocytes and microglia) are critical for the central nervous
system (CNS) in both physiological and pathological conditions. With this in mind, several …
system (CNS) in both physiological and pathological conditions. With this in mind, several …
Substrate elasticity exerts functional effects on primary microglia
SJ Blaschke, S Demir, A König, JA Abraham… - Frontiers in cellular …, 2020 - frontiersin.org
Microglia—the brain's primary immune cells—exert a tightly regulated cascade of pro-and
anti-inflammatory effects upon brain pathology, either promoting regeneration or …
anti-inflammatory effects upon brain pathology, either promoting regeneration or …
Multi-functional platelet membrane-camouflaged nanoparticles reduce neuronal apoptosis and regulate microglial phenotype during ischemic injury
C Zhao, Q Chen, W Li, J Zhang, C Yang, D Chen - Applied Materials Today, 2022 - Elsevier
Cerebral ischemic injury is an important factor affecting the prognosis of acute ischemic
stroke (AIS). Neuronal apoptosis and the change in microglial phenotype have been …
stroke (AIS). Neuronal apoptosis and the change in microglial phenotype have been …
[HTML][HTML] Primary microglia cell cultures in translational research: strengths and limitations
Microglia are the resident macrophages in the central nervous system, accounting for 10-
15% of the cell mass in the brain. Next to their physiological role in development, monitoring …
15% of the cell mass in the brain. Next to their physiological role in development, monitoring …
The angiotensin II receptors type 1 and 2 modulate astrocytes and their crosstalk with microglia and neurons in an in vitro model of ischemic stroke
DN Olschewski, N Nazarzadeh, F Lange, AM Koenig… - BMC neuroscience, 2024 - Springer
Background Astrocytes are the most abundant cell type of the central nervous system and
are fundamentally involved in homeostasis, neuroprotection, and synaptic plasticity. This …
are fundamentally involved in homeostasis, neuroprotection, and synaptic plasticity. This …
Function of miR-21-5p derived from ADSCs-exos on the neuroinflammation after cerebral ischemia
C Liu, T Yin, M Zhang, Z Li, B Xu, H Lv, P Wang… - Journal of Stroke and …, 2024 - Elsevier
Introduction Cerebral ischemia (CI) induces a profound neuroinflammatory response, but the
underlying molecular mechanism remains unclear. Exosomes from adipose-derived stem …
underlying molecular mechanism remains unclear. Exosomes from adipose-derived stem …
Early‐life thermal stress mediates long‐term alterations in hypothalamic microglia
Stressful environmental events in early life have long‐lasting consequences on later stress
responses. We previously showed that heat conditioning of 3‐day‐old chicks during the …
responses. We previously showed that heat conditioning of 3‐day‐old chicks during the …
Charakterisierung primärer Mikroglia auf weichen, elastischen PDMS-basierten Substraten in-vitro als Modell des intrinsischen zerebralen Milieus
S Demir - 2023 - kups.ub.uni-koeln.de
Über streng regulierte entzündungshemmende und-fördernde Kaskaden sind Mikroglia, als
residente Immunzellen des Zentralen Nervensystems (ZNS), an einer Vielzahl …
residente Immunzellen des Zentralen Nervensystems (ZNS), an einer Vielzahl …