Neuromechanical principles define the properties and problems that shape neural solutions
for movement. Although the theoretical and experimental evidence is debated, we present …

In order to generate skilled and efficient actions, the motor system must find solutions to
several problems inherent in sensorimotor control, including nonlinearity, nonstationarity …

Extracting muscle synergies from surface electromyographic signals (sEMGs) during
exercises has been widely applied to evaluate motor control strategies. This study explores …

The experimental findings herein reported are aimed at gaining a perspective on the
complex neural events that follow lesions of the motor cortical areas. Cortical damage …

How rudimentary movements evolve into sophisticated ones during development remains
unclear. It is often assumed that the primitive patterns of neural control are suppressed …

Evidence suggests that the nervous system controls motor tasks using a low-dimensional
modular organization of muscle activation. However, it is not clear if such an organization …

The central nervous system (CNS) may produce coordinated motor outputs via the
combination of motor modules representable as muscle synergies. Identification of muscle …

The precision of skilled forelimb movement has long been presumed to rely on rapid
feedback corrections triggered by internally directed copies of outgoing motor commands …

In 1959 CP Snow delivered his now-famous Rede Lecture," The Two Cultures," a reflection
on the academy based on the premise that intellectual life was divided into two cultures: the …

Previous studies in neurologically intact subjects have shown that motor coordination can be
described by task-dependent combinations of a few muscle synergies, defined here as a …