[HTML][HTML] Acute lung injury–from pathophysiology to treatment

D Mokra - Physiological research, 2020 - ncbi.nlm.nih.gov
Acute lung injury is characterized by acute respiratory insufficiency with tachypnea, cyanosis
refractory to oxygen, decreased lung compliance, and diffuse alveolar infiltrates on chest X …

Lung microbiome: new insights into the pathogenesis of respiratory diseases

R Li, J Li, X Zhou - Signal transduction and targeted therapy, 2024 - nature.com
The lungs were long thought to be sterile until technical advances uncovered the presence
of the lung microbial community. The microbiome of healthy lungs is mainly derived from the …

Quality assurance procedures for mass spectrometry untargeted metabolomics. a review

D Dudzik, C Barbas-Bernardos, A García… - … of pharmaceutical and …, 2018 - Elsevier
Untargeted metabolomics, as a global approach, has already proven its great potential and
capabilities for the investigation of health and disease, as well as the wide applicability for …

HILIC‐MS for metabolomics: An attractive and complementary approach to RPLC‐MS

DQ Tang, L Zou, XX Yin, CN Ong - Mass spectrometry reviews, 2016 - Wiley Online Library
Hydrophilic interaction chromatography (HILIC) is an emerging separation mode of liquid
chromatography (LC). Using highly hydrophilic stationary phases capable of retaining …

Engineered extracellular vesicles derived from dermal fibroblasts attenuate inflammation in a murine model of acute lung injury

AI Salazar‐Puerta, MA Rincon‐Benavides… - Advanced …, 2023 - Wiley Online Library
Acute respiratory distress syndrome (ARDS) represents a significant burden to the
healthcare system, with≈ 200 000 cases diagnosed annually in the USA. ARDS patients …

[HTML][HTML] Maternal obesity and the human milk metabolome: associations with infant body composition and postnatal weight gain

E Isganaitis, S Venditti, TJ Matthews, C Lerin… - The American journal of …, 2019 - Elsevier
Background Maternal obesity is a risk factor for childhood obesity; this is a major public
health concern given that∼ 40% of pregnant women are either overweight or obese …

Maximal oxidative capacity during exercise is associated with skeletal muscle fuel selection and dynamic changes in mitochondrial protein acetylation

KA Overmyer, CR Evans, NR Qi, CE Minogue… - Cell metabolism, 2015 - cell.com
Maximal exercise-associated oxidative capacity is strongly correlated with health and
longevity in humans. Rats selectively bred for high running capacity (HCR) have improved …

Comparing clinical features and outcomes in mechanically ventilated patients with COVID-19 and acute respiratory distress syndrome

MW Sjoding, AJ Admon, AK Saha, SG Kay… - Annals of the …, 2021 - atsjournals.org
Rationale: Patients with severe coronavirus disease (COVID-19) meet clinical criteria for the
acute respiratory distress syndrome (ARDS), yet early reports suggested they differ …

[HTML][HTML] Biomarkers for the acute respiratory distress syndrome: how to make the diagnosis more precise

MI García-Laorden, JA Lorente, C Flores… - Annals of …, 2017 - ncbi.nlm.nih.gov
The acute respiratory distress syndrome (ARDS) is an acute inflammatory process of the
lung caused by a direct or indirect insult to the alveolar-capillary membrane. Currently …

Using omics approaches to understand pulmonary diseases

M Kan, M Shumyatcher, BE Himes - Respiratory research, 2017 - Springer
Omics approaches are high-throughput unbiased technologies that provide snapshots of
various aspects of biological systems and include: 1) genomics, the measure of DNA …