Combination therapy in hypertension: An update

S Kalra, B Kalra, N Agrawal - Diabetology & metabolic syndrome, 2010 - Springer
Meticulous control of blood pressure is required in patients with hypertension to produce the
maximum reduction in clinical cardiovascular end points, especially in patients with …

Irbesartan: a review of its use in hypertension and in the management of diabetic nephropathy

KF Croom, MP Curran, KL Goa, CM Perry - Drugs, 2004 - Springer
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with us Track your research Search Cart 1.Home 2.Drugs 3.Article Irbesartan A Review of its …

The efficacy and safety of low‐and high‐dose fixed combinations of irbesartan/hydrochlorothiazide in patients with uncontrolled systolic blood pressure on …

JM Neutel, E Saunders, GL Bakris… - The Journal of …, 2005 - Wiley Online Library
This multicenter, prospective, open‐label, single‐arm study determined the efficacy and
safety of irbesartan/hydrochlorothiazide (HCTZ) fixed combinations in patients (n= 1005) …

Long-term use and tolerability of irbesartan for control of hypertension

V Forni, G Wuerzner, M Pruijm… - Integrated blood pressure …, 2011 - Taylor & Francis
In this review, we discuss the pharmacological and clinical properties of irbesartan, a
noncompetitive angiotensin II receptor type 1 antagonist, successfully used for more than a …

The long-term antihypertensive activity and tolerability of irbesartan with hydrochlorothiazide

P Raskin, R Guthrie, JM Flack, RA Reeves… - Journal of human …, 1999 - nature.com
The long-term safety, tolerability, and antihypertensive effects of irbesartan/
hydrochlorothiazide (HCTZ) were assessed in hypertensive patients (seated diastolic blood …

Irbesartan: an updated review of its use in cardiovascular disorders

A Markham, CM Spencer, B Jarvis - Drugs, 2000 - Springer
Irbesartan interrupts the renin-angiotensin system via selective blockade of the angiotensin
II subtype 1 receptor; the latter being responsible for the pressor related effects of …

Efficacy and safety of irbesartan/HCTZ combination therapy as initial treatment for rapid control of severe hypertension

JM Neutel, SS Franklin, S Oparil… - The Journal of …, 2006 - Wiley Online Library
Severe hypertension is difficult to control. This prospective, randomized, double‐blind, active‐
controlled, multicenter trial compared efficacy and safety of once‐daily irbesartan …

Managing hypertension in patients with type 2 diabetes mellitus

PP Dobesh - American journal of health-system pharmacy, 2006 - academic.oup.com
Purpose. Current guideline recommendations for effective strategies to optimize the
treatment of patients with concomitant hypertension and type 2 diabetes mellitus are …

Cardiovascular drug therapy in the elderly: theoretical and practical considerations

BR Williams, J Kim - Drugs & aging, 2003 - Springer
The elderly population is expanding rapidly throughout the world. Hypertension, heart
disease and other cardiovascular disorders are prevalent conditions among this age group …

Comprehensive overview: efficacy, tolerability, and cost-effectiveness of irbesartan

F Gialama, N Maniadakis - Vascular Health and Risk Management, 2013 - Taylor & Francis
Background Hypertension represents a major health problem, affecting more than one
billion adults worldwide. Irbesartan, an angiotensin II receptor blocker, is considered to be a …