Sepsis: pathophysiology and clinical management

JE Gotts, MA Matthay - Bmj, 2016 - bmj.com
Sepsis, severe sepsis, and septic shock represent increasingly severe systemic
inflammatory responses to infection. Sepsis is common in the aging population, and it …

Sepsis and septic shock: New definitions, new diagnostic and therapeutic approaches

S Esposito, G De Simone, G Boccia, F De Caro… - Journal of global …, 2017 - Elsevier
Sepsis and septic shock are common life-threatening pathologies associated with high
mortality and substantial costs for healthcare system. Clinical guidelines and bundles for the …

Defining immunological dysfunction in sepsis: A requisite tool for precision medicine

JF Bermejo-Martin, D Andaluz-Ojeda, R Almansa… - Journal of Infection, 2016 - Elsevier
Objectives Immunological dysregulation is now recognised as a major pathogenic event in
sepsis. Stimulation of immune response and immuno-modulation are emerging approaches …

Importance of quality‐of‐life priorities and preferences surrounding treatment decision making in patients with cancer and oncology clinicians

CP Williams, E Miller‐Sonet, RD Nipp, AH Kamal… - Cancer, 2020 - Wiley Online Library
Background Shared decision‐making (SDM) occurs when a patient partners with their
oncologist to integrate personal preferences and values into treatment decisions. A key …

Population-based epidemiology of sepsis in a subdistrict of Beijing

J Zhou, H Tian, X Du, X Xi, Y An, M Duan… - Critical care …, 2017 - journals.lww.com
Objective: Information about the epidemiology of sepsis in community residents in China
remains scarce and incomplete. The purpose of this study was to describe the occurrence …

Associations of obesity and lifestyle with the risk and mortality of bloodstream infection in a general population: a 15-year follow-up of 64 027 individuals in the HUNT …

J Paulsen, Å Askim, RM Mohus, A Mehl… - International Journal …, 2017 - academic.oup.com
Background Bloodstream infections (BSI) cause considerable morbidity and mortality, and
primary prevention should be a priority. Lifestyle factors are of particular interest since they …

A systematic review on risk factors associated with sepsis in patients admitted to intensive care units

M Fathi, N Markazi-Moghaddam… - Australian Critical Care, 2019 - Elsevier
Objective We sought to systematically review data on the risk factors influencing the
incidence of sepsis in patients admitted to intensive care units (ICUs). Review methods An …

Association between sepsis incidence and regional socioeconomic deprivation and health care capacity in Germany–an ecological study

N Rose, C Matthäus-Krämer, D Schwarzkopf… - BMC Public Health, 2021 - Springer
Background Sepsis is a substantial health care burden. Data on regional variation in sepsis
incidence in Germany and any possible associations with regional socioeconomic …

Rapid systematic review on risks and outcomes of sepsis: the influence of risk factors associated with health inequalities

S Bladon, D Ashiru-Oredope, N Cunningham… - International Journal for …, 2024 - Springer
Background and aims Sepsis is a serious and life-threatening condition caused by a
dysregulated immune response to an infection. Recent guidance issued in the UK gave …

Association of iron status with the risk of bloodstream infections: results from the prospective population-based HUNT Study in Norway

RM Mohus, J Paulsen, L Gustad, Å Askim, A Mehl… - Intensive care …, 2018 - Springer
Purpose As iron is essential for both immune function and microbial growth, alterations in
iron status could influence the risk of infections. We assessed the associations of iron status …