Characterization of two melanoma cell lines resistant to BRAF/MEK inhibitors (vemurafenib and cobimetinib)

M Kot, A Simiczyjew, J Wądzyńska, M Ziętek… - Cell Communication and …, 2024 - Springer
Background BRAF (v-raf murine sarcoma viral oncogene homolog B1)/MEK (mitogen-
activated protein kinase kinase) inhibitors are used for melanoma treatment. Unfortunately …

Exploring the molecular mechanisms of curcumin in modulating memory impairment in neurodegenerative disorders

Y Baghcheghi, F Razazpour, F Mirzaee… - Molecular Biology …, 2025 - Springer
Introduction Memory impairment is a critical challenge in neurodegenerative disorders,
particularly in Alzheimer's disease, Parkinson's disease, and age-related cognitive decline …

A multifactorial lens on risk factors promoting the progression of Alzheimer's disease

J Parker, JM Moris, LC Goodman, VK Paidisetty… - Brain Research, 2024 - Elsevier
The prevalence of Alzheimer's disease (AD) among adults has continued to increase over
the last two decades, which has sparked a significant increase in research that focuses on …

Microneedles integrated with atorvastatin-loaded pumpkisomes for breast cancer therapy: A localized delivery approach

LA Heikal, AA Ashour, AR Aboushanab… - Journal of Controlled …, 2024 - Elsevier
Breast cancer is the most common invasive cancer in women worldwide, having a significant
impact on women's well-being. Early diagnosis of breast cancer followed by appropriate …