In mammals, neurogenesis occurs during both embryonic and postnatal development. In eutherians, most brain structures develop embryonically; conversely, in marsupials, a …
Hippocampal neurogenesis has typically been studied during embryonic development or in adulthood, promoting the perception of two distinct phenomena. We propose a perspective …
Variations in size and complexity of the cerebral cortex result from differences in neuron number and composition, rooted in evolutionary changes in direct and indirect neurogenesis …
UJ Kim, N Hong, JC Ahn - International Journal of Molecular Sciences, 2022 - mdpi.com
Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by social communication and interaction disorders, as well as repetitive and restrictive behaviors. To …
G Berdugo‐Vega, S Dhingra, F Calegari - The EMBO Journal, 2023 - embopress.org
For decades, the mammalian hippocampus has been the focus of cellular, anatomical, behavioral, and computational studies aimed at understanding the fundamental …
In the mammalian brain, neurogenesis is maintained throughout adulthood primarily in two typical niches, the subgranular zone (SGZ) of the dentate gyrus and the subventricular zone …
LC Abbott, F Nigussie - International Journal of Molecular Sciences, 2021 - mdpi.com
The mammalian brain is formed from billions of cells that include a wide array of neuronal and glial subtypes. Neural progenitor cells give rise to the vast majority of these cells during …
C Milazzo, EJ Mientjes, I Wallaard, SV Rasmussen… - JCI insight, 2021 - ncbi.nlm.nih.gov
Angelman syndrome (AS) is a severe neurodevelopmental disorder for which only symptomatic treatment with limited benefits is available. AS is caused by mutations affecting …
Z Finkel, F Esteban, B Rodriguez, T Fu, X Ai, L Cai - Cells, 2021 - mdpi.com
Adult neural stem and progenitor cells (NSPCs) contribute to learning, memory, maintenance of homeostasis, energy metabolism and many other essential processes. They …