Lactate oxidase (LOx) has attracted extensive interest in cancer diagnosis and therapy in
recent years owing to its specific catalysis on l‐lactate; its catalytic process consumes …

Lactate in tumors has long been considered “metabolic junk” derived from the glycolysis of
cancer cells and utilized only as a biomarker of malignancy, but is presently believed to be a …

Porous organic frameworks (POFs) have become a highly sought-after research domain that
offers a promising avenue for developing cutting-edge nanostructured materials, both in …

Colonization of cancer cells at secondary sites, a decisive step in tumor metastasis, is
strongly dependent on the formation of metastatic microenvironments regulated by intrinsic …

Increasing numbers of studies have shown that tumor cells prefer fermentative glycolysis
over oxidative phosphorylation to provide a vast amount of energy for fast proliferation even …

Radiation therapy (RT) is one of the most widely used cancer treatments. However, the
vigorous biosynthesis of cancer cells plays an important role for RT resistance. Herein, we …

Reprogramming of tumor associated macrophages (TAMs) from M2 to M1 phenotype is
becoming a feasible strategy for tumor immunotherapy, however, its efficacy is potentially …

Reticular chemistry is the chemistry of linking molecular building units through strong bonds
to create extended crystalline structures, such as metal–organic frameworks, hydrogen …

Traditionally referred to as “metabolic junk”, lactate has now been recognized as essential
“energy currency” and crucial “messenger” that contributes to tumor evolution …

Glycolytic reprogramming is emerging as a hallmark of various cancers and a promising
therapeutic target. Nanotechnology is revolutionizing the anti-tumor therapeutic approaches …