Hydrogel microparticles for biomedical applications

AC Daly, L Riley, T Segura, JA Burdick - Nature Reviews Materials, 2020 - nature.com
Hydrogel microparticles (HMPs) are promising for biomedical applications, ranging from the
therapeutic delivery of cells and drugs to the production of scaffolds for tissue repair and …

Modeling physiological events in 2D vs. 3D cell culture

K Duval, H Grover, LH Han, Y Mou… - …, 2017 - journals.physiology.org
Cell culture has become an indispensable tool to help uncover fundamental biophysical and
biomolecular mechanisms by which cells assemble into tissues and organs, how these …

[HTML][HTML] Microgel assembly: Fabrication, characteristics and application in tissue engineering and regenerative medicine

Q Feng, D Li, Q Li, X Cao, H Dong - Bioactive materials, 2022 - Elsevier
Microgel assembly, a macroscopic aggregate formed by bottom-up assembly of microgels, is
now emerging as prospective biomaterials for applications in tissue engineering and …

[HTML][HTML] Advancements in hydrogel design for articular cartilage regeneration: A comprehensive review

F Hashemi-Afzal, H Fallahi, F Bagheri, MN Collins… - Bioactive Materials, 2025 - Elsevier
This review paper explores the cutting-edge advancements in hydrogel design for articular
cartilage regeneration (CR). Articular cartilage (AC) defects are a common occurrence …

3D bioprinting of tumor models for cancer research

Y Kang, P Datta, S Shanmughapriya… - ACS Applied Bio …, 2020 - ACS Publications
The exact mechanistic understanding of cancer metastasis continues to be unknown,
although it is a major cause of death worldwide. Along with the tumor mass, the tumor …

Designing microgels for cell culture and controlled assembly of tissue microenvironments

AS Caldwell, BA Aguado… - Advanced functional …, 2020 - Wiley Online Library
Micrometer‐sized hydrogels, termed microgels, are emerging as multifunctional platforms
that can recapitulate tissue heterogeneity in engineered cell microenvironments. The …

Design of injectable materials to improve stem cell transplantation

LM Marquardt, SC Heilshorn - Current stem cell reports, 2016 - Springer
Stem cell-based therapies are steadily gaining traction for regenerative medicine
approaches to treating disease and injury throughout the body. While a significant body of …

Opportunities for multicomponent hybrid hydrogels in biomedical applications

HK Lau, KL Kiick - Biomacromolecules, 2015 - ACS Publications
Hydrogels provide mechanical support and a hydrated environment that offer good
cytocompatibility and controlled release of molecules, and myriad hydrogels thus have been …

Liquid–liquid two-phase systems for the production of porous hydrogels and hydrogel microspheres for biomedical applications: a tutorial review

DL Elbert - Acta biomaterialia, 2011 - Elsevier
Macroporous hydrogels may have direct applications in regenerative medicine as scaffolds
to support tissue formation. Hydrogel microspheres may be used as drug-delivery vehicles …

Assembly of PEG microgels into porous cell‐instructive 3D scaffolds via thiol‐ene click chemistry

S Xin, OM Wyman, DL Alge - Advanced healthcare materials, 2018 - Wiley Online Library
The assembly of microgel building blocks into 3D scaffolds is an emerging strategy for tissue
engineering. A key advantage is that the inherent microporosity of these scaffolds provides …