In the two decades since the introduction of the “click chemistry” concept, the toolbox of “click
reactions” has continually expanded, enabling chemists, materials scientists, and biologists …

Aryl transfer reactions from arenediazonium salts have started to make their impact in
chemical biology with initial forays in the arena of arylative modifications and bio …

Chemoselective modification of complex biomolecules has become a cornerstone of
chemical biology. Despite the exciting developments of the past two decades, the demand …

A metal-free, light-induced regiodivergent functionalization of α, β-unsaturated amides with
aryltriazenes under ambient conditions was developed. The visible light and B (C6F5) 3 …

Peptide–receptor interactions play critical roles in a wide variety of physiological processes.
Methods to link bioactive peptides covalently to unmodified receptors on the surfaces of …

This work describes the development of phenyl diazenyl piperidine triazene derivatives that
can be activated to release aryl diazonium ions for labeling of proteins using light. These …

Aryl diazonium ions have long been used in bioconjugation due to their reactivity toward
electron-rich aryl residues, such as tyrosine. However, their utility in biological systems has …

The use of small‐molecule fluorophores to label proteins with minimal perturbation in
response to an external stimulus is a powerful tool to probe chemical and biochemical …

Aryl diazonium cations are versatile bioconjugation reagents due to their reactivity towards
electron‐rich aryl residues and secondary amines, but historically their usage has been …

Aryl diazonium ions are useful across a range of chemical/biochemical areas. These
species are generally made using strongly acidic conditions, which can be detrimental to …