Progress in the development of subunit vaccines for gastrointestinal nematodes of ruminants

JB Matthews, P Geldhof, T Tzelos… - Parasite …, 2016 - Wiley Online Library
The global increase in anthelmintic resistant nematodes of ruminants, together with
consumer concerns about chemicals in food, necessitates the development of alternative …

Recent developments in livestock and wildlife brucellosis vaccination.

SC Olsen - Revue scientifique et technique (International Office of …, 2013 - europepmc.org
Live attenuated brucellosis vaccines have been available for protecting domestic livestock
against Brucella melitensis and B. abortus for more than 60 years. Current vaccines are …

A resource for improved predictions of Trypanosoma and Leishmania protein three-dimensional structure

RJ Wheeler - PLoS One, 2021 - journals.plos.org
AlphaFold2 and RoseTTAfold represent a transformative advance for predicting protein
structure. They are able to make very high-quality predictions given a high-quality alignment …

Vaccines against bovine babesiosis: where we are now and possible roads ahead

M Florin-Christensen, CE Suarez, AE Rodriguez… - Parasitology, 2014 - cambridge.org
Bovine babesiosis caused by the tick-transmitted haemoprotozoans Babesia bovis, Babesia
bigemina and Babesia divergens commonly results in substantial cattle morbidity and …

Proteomic identification of novel cytoskeletal proteins associated with TbPLK, an essential regulator of cell morphogenesis in Trypanosoma brucei

MR McAllaster, KN Ikeda… - Molecular biology of …, 2015 - Am Soc Cell Biol
Trypanosoma brucei is the causative agent of African sleeping sickness, a devastating
disease endemic to sub-Saharan Africa with few effective treatment options. The parasite is …

[PDF][PDF] An alternative strategy for trypanosome survival in the mammalian bloodstream revealed through genome and transcriptome analysis of the ubiquitous bovine …

S Kelly, A Ivens, GA Mott, E O'Neill… - Genome Biology and …, 2017 - academic.oup.com
There are hundreds of Trypanosoma species that live in the blood and tissue spaces of their
vertebrate hosts. The vast majority of these do not have the ornate system of antigenic …

Major Surface Antigens in Zoonotic Babesia

S Delbecq - Pathogens, 2022 - mdpi.com
Human babesiosis results from a combination of tick tropism for humans, susceptibility of a
host to sustain Babesia development, and contact with infected ticks. Climate modifications …

An epidemiological survey of vector-borne pathogens infecting cattle in Kyrgyzstan

A Zhyldyz, K Aitakin, B Atabek, J Elmurat… - Parasitology …, 2023 - Elsevier
Cattle production is a major contributor to the national economy of Kyrgyzstan. Most cattle in
Kyrgyzstan are managed via extensive systems and graze in communal pastures. As a …

Modulation of the Immune Response by Nematode Secreted Acetylcholinesterase Revealed by Heterologous Expression in Trypanosoma musculi

R Vaux, C Schnoeller, R Berkachy, LB Roberts… - PLoS …, 2016 - journals.plos.org
Nematode parasites secrete molecules which regulate the mammalian immune system, but
their genetic intractability is a major impediment to identifying and characterising the …

Serum biochemical parameters and cytokine profiles associated with natural African trypanosome infections in cattle

SM Bakari, JA Ofori, KA Kusi, GK Aning… - Parasites & vectors, 2017 - Springer
Abstract Background Animal African trypanosomiasis (AAT) greatly affects livestock
production in sub-Saharan Africa. In Ghana prevalence of AAT is estimated to range …