NASA's plans for space exploration include a return to the Moon to stay—boots back on the
lunar surface with an orbital outpost. This station will be a launch point for voyages to …

As human space exploration advances to establish a permanent presence beyond the Low
Earth Orbit (LEO) with NASA's Artemis mission, researchers are striving to understand and …

Stressors ranging from psychogenic/social to neurogenic/injury to systemic/microbial can
impact microglial inflammatory processes, but less is known regarding their effects on …

Abstract Space is an isolated, confined environment for humans. These conditions can have
numerous effects on astronaut mental health and safety. Psychological and social issues …

Epigenetic mechanisms occurring in the brain as well as alterations in the gut microbiome
composition might contribute to Alzheimer's disease (AD). Human amyloid precursor protein …

In the coming decade, astronauts will travel back to the moon in preparation for future Mars
missions. Exposure to galactic cosmic radiation (GCR) is a major obstacle for deep space …

For missions beyond low Earth orbit to the moon or Mars, space explorers will encounter a
complex radiation field composed of various ion species with a broad range of energies …

Staying longer in outer space will inevitably increase the health risks of astronauts due to the
exposures to galactic cosmic rays and solar particle events. Exposure may pose a significant …

Spaceflight poses risks to the central nervous system (CNS), and understanding
neurological responses is important for future missions. We report CNS changes in …

The gut microbiome and the gut brain axis are potential determinants of Alzheimer's disease
(AD) etiology or severity and gut microbiota might coordinate with the gut-brain axis to …