Modern thrombophilia testing fails to identify any underlying prothrombotic tendency in a
significant number of patients presenting with objectively confirmed venous …

Factor VIII: C levels show a familial clustering, which remains after adjustment for the
influence of vWF and blood group. 46 Analysis of familial aggregation of factor VIII levels …

Background A high plasma level of factor VIII is a risk factor for venous thromboembolism.
We evaluated the risk of a recurrence of thrombosis after an initial episode of spontaneous …

PURPOSE: We sought to assess prospectively whether higher levels of blood coagulation
factors and inflammation markers are risk factors for venous thromboembolism. SUBJECTS …

During the past decade, the role of inflammation in the pathophysiology of arterial
thrombosis has been elucidated. However, comparatively little is known about the …

Venous thrombosis, whose main clinical presentations include deep vein thrombosis and
pulmonary embolism, represents a major health problem worldwide. Numerous conditions …

Venous thromboembolism is a serious disorder because of its potential complications, such
as pulmonary embolism and the post-thrombotic syndrome. Inherited determinants of …

There is strong evidence linking venous thromboembolic events and malignancy.
Laboratory markers of coagulation activation such as thrombin–antithrombin complex or …

Objective—Patients with cancer are at an increased risk for venous thromboembolism (VTE).
Clotting factor VIII activity (FVIII) has been established as risk factor of primary and recurrent …

Hypercoagulability can be defined as the tendency to have thrombosis as a result of certain
inherited and/or acquired molecular defects. Clinical manifestations of hypercoagulability …