Because germline mutations are the source of all evolutionary adaptations and heritable
diseases, characterizing their properties and the rate at which they arise across individuals …

Most of the human pandemics reported to date can be classified as zoonoses. Among these,
there is a long history of infectious diseases that have spread from non-human primates …

Abstract 'Orang-utan'is derived from a Malay term meaning 'man of the forest'and aptly
describes the southeast Asian great apes native to Sumatra and Borneo. The orang-utan …

Human Evolutionary Genetics is a groundbreaking text which for the first time brings
together molecular genetics and genomics to the study of the origins and movements of …

During the past four decades, the molecular-clock hypothesis has provided an invaluable
tool for building evolutionary timescales, and has served as a null model for testing …

Humans and their closest evolutionary relatives, the chimpanzees, differ in∼ 1.24% of their
genomic DNA sequences. The fraction of these changes accumulated during the speciation …

Class 2, or DNA transposons, make up∼ 3% of the human genome, yet the evolutionary
history of these elements has been largely overlooked and remains poorly understood. Here …

We investigated the evolution of the families of LINE-1 (L1) retrotransposons that have
amplified in the human lineage since the origin of primates. We identified two phases in the …

Human evolution is characterized by a dramatic increase in brain size and complexity. To
probe its genetic basis, we examined the evolution of genes involved in diverse aspects of …

With genomic data, alignments can be assembled that greatly increase the number of
informative sites for analysis of molecular divergence dates. Here, we present an estimate of …