▪ Abstract Growing evidence has indicated that cellular reduction/oxidation (redox) status
regulates various aspects of cellular function. Oxidative stress can elicit positive responses …

▪ Abstract The mammalian thioredoxins are a family of small (approximately 12 kDa) redox
proteins that undergo NADPH-dependent reduction by thioredoxin reductase and in turn …

Epstein-Barr virus (EBV) encodes genes that ensure its persistence in human B
lymphocytes. Some of the genes encourage B-cell proliferation; others are poised to evade …

The thioredoxins are ubiquitous proteins containing a conserved-Trp-Cys-Gly-Pro-Cys-Lys-
redox catalytic site. Mammalian thioredoxin family members include thioredoxin-1 (Trx1) …

The transcription factors NF-kappa B and AP-1 have been implicated in the inducible
expression of a variety of genes involved in responses to oxidative stress and cellular …

HTLV‐I transformed T cells not only express a large number of interleukin‐2 receptors [IL‐
2R/p55 (Tac)], but also produce a factor named ATL‐derived factor (ADF) that augments the …

A nasopharyngeal carcinoma tumour (designated C15) propagated in nude mice has been
used to generate a large cDNA library that we have analysed for Epstein‐Barr virus (EBV) …

Interleukin 1 (IL-1) has been obtained from the Epstein-Barr virus-infected B-lymphoblastoid
cell line 3B6 and shown to be involved in autocrine growth of 3B6 B cells. Independently …

Thioredoxin is the best representative enzyme of a group of proteins, widely distributed and
possessing dithiol-disulfide oxidoreductase activity. We have constructed a cDNA library …

Soluble products of either Epstein-Barr virus (EBV)-infected B cells or activated monocytes
promote the proliferation of EBV-infected B cells and permit their growth at low cell densities …