Infections caused by non-tuberculous mycobacteria (NTM) are increasing globally and are
notoriously difficult to treat due to intrinsic resistance of these bacteria to many common …

Transporters of the RND superfamily are well-known as the major drug efflux pumps of Gram-
negative bacteria. However, they are widespread in organisms ranging from Archaea to …

Iron is an essential nutrient for most bacterial pathogens, but is restricted by the host immune
system. Mycobacterium tuberculosis (Mtb) utilizes two classes of small molecules …

The highly contagious disease tuberculosis (TB) is caused by the bacterium Mycobacterium
tuberculosis (Mtb), which has been evolving drug resistance at an alarming rate. Like all …

Mycolic acids are vital components of the cell wall of the tubercle bacillus Mycobacterium
tuberculosis and are required for viability and virulence. While mycolic acid biosynthesis is …

Mycobacterial genomes contain large sets of loci encoding membrane proteins that belong
to a family of multidrug resistance pumps designated Resistance‐Nodulation‐Cell Division …

Mycobacterium abscessus is a rapidly-growing species causing a diverse panel of clinical
manifestations, ranging from cutaneous infections to severe respiratory disease. Its unique …

The biology of mycobacteria is dominated by a complex cell envelope of unique composition
and structure and of exceptionally low permeability. This cell envelope is the basis of many …

Siderophores are small iron-binding molecules secreted by bacteria to scavenge iron.
Mycobacterium tuberculosis (Mtb), the etiologic agent of tuberculosis, produces the …

In mycobacteria, M mp L proteins represent key components that participate in the
biosynthesis of the complex cell envelope. Whole genome analysis of a spontaneous rough …