The glutamate system as a crucial regulator of CNS toxicity and survival of HIV reservoirs
AM Gorska, EA Eugenin - Frontiers in cellular and infection …, 2020 - frontiersin.org
Glutamate (Glu) is the most abundant excitatory neurotransmitter in the central nervous
system (CNS). HIV-1 and viral proteins compromise glutamate synaptic transmission …
system (CNS). HIV-1 and viral proteins compromise glutamate synaptic transmission …
Antisense transcripts and antisense protein: a new perspective on human immunodeficiency virus type 1
J Savoret, JM Mesnard, A Gross, N Chazal - Frontiers in Microbiology, 2021 - frontiersin.org
It was first predicted in 1988 that there may be an Open Reading Frame (ORF) on the
negative strand of the Human Immunodeficiency Virus type 1 (HIV-1) genome that could …
negative strand of the Human Immunodeficiency Virus type 1 (HIV-1) genome that could …
A child with perinatal HIV infection and long-term sustained virological control following antiretroviral treatment cessation
Understanding HIV remission in rare individuals who initiated antiretroviral therapy (ART)
soon after infection and then discontinued, may inform HIV cure interventions. Here we …
soon after infection and then discontinued, may inform HIV cure interventions. Here we …
Impaired Priming of SARS-CoV-2-Specific Naive CD8+ T Cells in Older Subjects
E Gallerani, D Proietto, B Dallan… - Frontiers in …, 2021 - frontiersin.org
Advanced age is associated with severe symptoms and death upon SARS-CoV-2 infection.
Virus-specific CD8+ T-cell responses have shown to be protective toward critical COVID-19 …
Virus-specific CD8+ T-cell responses have shown to be protective toward critical COVID-19 …
In chronic hepatitis C infection, myeloid-derived suppressor cell accumulation and T cell dysfunctions revert partially and late after successful direct-acting antiviral …
V Telatin, F Nicoli, C Frasson, N Menegotto… - Frontiers in cellular …, 2019 - frontiersin.org
Chronic HCV infection is characterized by several immunological alterations, such as the
accumulation of suppressor cells and of hyperactivated T lymphocytes. However, it is …
accumulation of suppressor cells and of hyperactivated T lymphocytes. However, it is …
Age-related decline of de novo T cell responsiveness as a cause of COVID-19 severity
To the Editor, So far, little attention has been paid to the link between immunosenescence
and the dramatic mortality rate of coronavirus disease 2019 (COVID-19) in older age groups …
and the dramatic mortality rate of coronavirus disease 2019 (COVID-19) in older age groups …
HPV-specific systemic antibody responses and memory B cells are independently maintained up to 6 years and in a vaccine-specific manner following immunization …
F Nicoli, B Mantelli, E Gallerani, V Telatin, I Bonazzi… - Vaccines, 2020 - mdpi.com
Human papillomavirus (HPV) persistent infections are associated with cervical cancer and
other HPV-related diseases and tumors. Thus, the characterization of long lasting immunity …
other HPV-related diseases and tumors. Thus, the characterization of long lasting immunity …
T-cell evasion and invasion during HIV-1 infection: the role of HIV-1 Tat protein
T-cell-mediated immune responses play indispensable roles in the defense against
infectious pathogens including human immunodeficiency virus type 1 (HIV-1) which can …
infectious pathogens including human immunodeficiency virus type 1 (HIV-1) which can …
The HIV-1 Tat protein affects human CD4+ T-cell programing and activation, and favors the differentiation of naïve CD4+ T cells
F Nicoli, E Gallerani, F Sforza, V Finessi, M Chachage… - Aids, 2018 - journals.lww.com
Objective: HIV infection is characterized by several immune dysfunctions, such as chronic
activation of the immune system, premature aging and loss of CD4+ T cells, in particular …
activation of the immune system, premature aging and loss of CD4+ T cells, in particular …
The Tat Protein of HIV-1 Prevents the Loss of HSV-Specific Memory Adaptive Responses and Favors the Control of Viral Reactivation
F Nicoli, E Gallerani, M Sicurella, S Pacifico, A Cafaro… - Vaccines, 2020 - mdpi.com
The development of therapeutic strategies to control the reactivation of the Herpes Simplex
Virus (HSV) is an unaddressed priority. In this study, we evaluated whether Tat, a HIV-1 …
Virus (HSV) is an unaddressed priority. In this study, we evaluated whether Tat, a HIV-1 …