In the body, cells encounter a complex milieu of signals, including topographical cues, in the
form of the physical features of their surrounding environment. Imposed topography can …

Adult neurogenesis is a widespread trait of vertebrates; however, the degree of this ability
and the underlying activity of the adult neural stem cells differ vastly among species. In …

Investigations of adult neurogenesis in recent years have revealed numerous differences
among mammalian species, reflecting the remarkable diversity in brain anatomy and …

There are 64,000 living species of vertebrates on our planet and all of them have a heart.
Comparative analyses devoted to understanding the regenerative potential of the …

The opossum (Monodelphis domestica), with its sequenced genome, ease of laboratory
care and experimental manipulation, and unique biology, is the most used laboratory …

Two central challenges for the field of neurobiology are to understand how axons grow and
make proper synaptic connections under normal conditions and how they repair their …

Primary dissociated neuronal cultures have become a standard model for studying central
nervous system (CNS) development. Such cultures are predominantly prepared from the …

Axon degeneration is the pivotal pathological event of acute traumatic neural injury as well
as many chronic neurodegenerative diseases. It is an active cellular program and yet …

Despite the potential importance that synapse regeneration plays in restoring neuronal
function after spinal cord injury (SCI), even the most basic questions about the morphology …

Regeneration is a strategy to maintain form and function throughout life. Studies carried out
on animal models throughout the phylogenetic tree have flourished in the last decades in …