Background: Global or untargeted metabolomics is widely used to comprehensively
investigate metabolic profiles under various pathophysiological conditions such as …

Simple Summary The gold standard for detecting cancer and profiling tumors is tissue
biopsies. Despite this, tissue biopsies have been associated with many limitations leading to …

Early, express, and reliable detection of cancer can provide a favorable prognosis and
decrease mortality. Tumor biomarkers have been proven to be closely related to tumor …

Extracellular vesicles (EVs) can contain DNA, RNA, proteins and metabolic molecules from
primary origins; they are coated with a phospholipid bilayer membrane and released by …

Ischemic stroke (IS) is a multifactorial and heterogeneous neurological disorder with high
rate of death and long-term impairment. Despite years of studies, there are still no stroke …

Pharmaceutical analysis refers to an area of analytical chemistry that deals with active
compounds either by themselves (drug substance) or when formulated with excipients (drug …

The emerging disciplines of lipidomics and metabolomics show great potential for the
discovery of diagnostic biomarkers, but appropriate pre-analytical sample-handling …

In recent years, liquid biopsy has emerged as an alternative method to diagnose and
monitor tumors. Compared to classical tissue biopsy procedures, liquid biopsy facilitates the …

Accurate diagnosis of chronic obstructive pulmonary disease (COPD) and exacerbations by
metabolic biomarkers enables individualized treatment. Advanced metabolic detection …

Recent studies have shown a growing interest in the complex relationship between the
human gut microbiota, metabolism, and overall health. This review aims to explore the gut …