The vimentin gene (VIM) encodes one of the 71 human intermediate filament (IF) proteins,
which are the building blocks of highly ordered, dynamic, and cell type-specific fiber …

Vimentin is a protein that has been linked to a large variety of pathophysiological conditions,
including cataracts, Crohn's disease, rheumatoid arthritis, HIV and cancer. Vimentin has also …

Somatic cells that change from one mature phenotype to another exhibit the property of
plasticity. It is increasingly clear that epithelial and endothelial cells enjoy some of this …

Tumours are known as wounds that do not heal—this implies that cells that are involved in
angiogenesis and the response to injury, such as endothelial cells and fibroblasts, have a …

A large proportion of the cytoplasm of vertebrate cells, normal or transformed, is represented
by components of the cytoskeleton, including actin-containing microfilaments, tubulin …

Intracellular deposition of misfolded protein aggregates into ubiquitin-rich cytoplasmic
inclusions is linked to the pathogenesis of many diseases. Why these aggregates form …

Myeloid cells are a major cellular compartment of the immune system comprising
monocytes, dendritic cells, tissue macrophages, and granulocytes. Models of cellular …

In this paper we present keratin expression data that lend strong support to a model of
corneal epithelial maturation in which the stem cells are located in the limbus, the …

Tumors are unorganized organs that contain many different cell types. In the recent years,
many studies have reported that primary tumors contain fibroblasts/myofibroblasts …

Cells of the inner layers of the epidermis contain small keratins (46~ 56K), whereas the cells
of the outer layers contain large keratins (63-6710 in addition to small ones. The changes in …