[HTML][HTML] Fibro-adipogenic progenitors in physiological adipogenesis and intermuscular adipose tissue remodeling

M Flores-Opazo, D Kopinke, F Helmbacher… - Molecular Aspects of …, 2024 - Elsevier
Excessive accumulation of intermuscular adipose tissue (IMAT) is a common pathological
feature in various metabolic and health conditions and can cause muscle atrophy, reduced …

RhoA/ROCK2 signalling is enhanced by PDGF‐AA in fibro‐adipogenic progenitor cells: implications for Duchenne muscular dystrophy

E Fernández‐Simón, X Suárez‐Calvet… - Journal of Cachexia …, 2022 - Wiley Online Library
Background The lack of dystrophin expression in Duchenne muscular dystrophy (DMD)
induces muscle fibre and replacement by fibro‐adipose tissue. Although the role of some …

Identification of auxiliary biomarkers and description of the immune microenvironmental characteristics in duchenne muscular dystrophy by bioinformatical analysis …

X Han, J Han, N Wang, G Ji, R Guo, J Li… - Frontiers in …, 2022 - frontiersin.org
Background Duchenne muscular dystrophy (DMD) is a genetic muscle disorder
characterized by progressive muscle wasting associated with persistent inflammation. In this …

Transcriptomic analysis of paired healthy human skeletal muscles to identify modulators of disease severity in DMD

S Nieves-Rodriguez, F Barthélémy, JD Woods… - Frontiers in …, 2023 - frontiersin.org
Muscle damage and fibro-fatty replacement of skeletal muscles is a main pathologic feature
of Duchenne muscular dystrophy (DMD) with more proximal muscles affected earlier and …

Large scale serum proteomics identifies proteins associated with performance decline and clinical milestones in Duchenne muscular dystrophy

NA Ikelaar, AM Barnard, SWM Eng, SH Vajargah… - medRxiv, 2024 - pmc.ncbi.nlm.nih.gov
Serum biomarkers are promising minimally invasive outcome measures in clinical studies in
Duchenne muscular dystrophy (DMD). However, biomarkers strongly associated with …

Transcriptomic Analysis of Healthy Skeletal Muscle to Identify Modulators of Differential Skeletal Muscle Susceptibility in Duchenne Muscular Dystrophy

SN Rodríguez - 2023 - search.proquest.com
Duchenne muscular dystrophy (DMD) is a progressive muscle disease caused by mutations
in the DMD gene encoding for the structural muscle protein dystrophin. Absence of …