Polyethylene glycols (PEG s) or macrogols are polyether compounds widely used in medical
and household products. Although generally considered biologically inert, cases of mild to …

Perioperative immediate hypersensitivity reactions are rare. Subsequent allergy
investigation is complicated by multiple simultaneous drug exposures, the use of drugs with …

Background Anaphylaxis during anaesthesia is a serious complication for patients and
anaesthetists. Methods The 6th National Audit Project (NAP6) on perioperative anaphylaxis …

This is the fourth iteration of this parameter entitled “The Diagnosis and Management of
Anaphylaxis.” The first anaphylaxis parameter was published in 1998 and the last in 2010 …

Skin tests are of paramount importance for the evaluation of drug hypersensitivity reactions.
Drug skin tests are often not carried out because of lack of concise information on specific …

Drug hypersensitivity reactions (DHR s) are a matter of great concern, both for outpatient
and in hospital care. The evaluation of these patients is complex, because in vivo tests have …

Suspected perioperative allergic reactions are rare but can be life-threatening. The
diagnosis is difficult to make in the perioperative setting, but prompt recognition and correct …

Background Polyethylene glycols (PEGs) are polymers of varying molecular weight (MW)
used widely as excipients in drugs and other products, including the mRNA vaccines against …

Suspected perioperative hypersensitivity reactions are rare but contribute significantly to the
morbidity and mortality of surgical procedures. Recent publications have highlighted the …

Anaphylaxis is an acute, life-threatening, multisystem syndrome resulting from the sudden
release of mediators by mast cells and basophils. Although anaphylaxis is often under …