Memory B cells
T Kurosaki, K Kometani, W Ise - Nature Reviews Immunology, 2015 - nature.com
The immune system can remember a previously experienced pathogen and can evoke an
enhanced response to reinfection that depends on memory lymphocyte populations. Recent …
enhanced response to reinfection that depends on memory lymphocyte populations. Recent …
Extrahepatic morbidity and mortality of chronic hepatitis C
Chronic hepatitis C virus (HCV) infection is associated with several extrahepatic
manifestations. Patients with HCV may develop mixed cryoglobulinemia and its sequelae …
manifestations. Patients with HCV may develop mixed cryoglobulinemia and its sequelae …
Comprehensive mapping of immune perturbations associated with severe COVID-19
L Kuri-Cervantes, MB Pampena, W Meng… - Science …, 2020 - science.org
Although critical illness has been associated with SARS-CoV-2–induced hyperinflammation,
the immune correlates of severe COVID-19 remain unclear. Here, we comprehensively …
the immune correlates of severe COVID-19 remain unclear. Here, we comprehensively …
[HTML][HTML] Atypical B cells are part of an alternative lineage of B cells that participates in responses to vaccination and infection in humans
The diversity of circulating human B cells is unknown. We use single-cell RNA sequencing
(RNA-seq) to examine the diversity of both antigen-specific and total B cells in healthy …
(RNA-seq) to examine the diversity of both antigen-specific and total B cells in healthy …
What are the benefits of a sustained virologic response to direct-acting antiviral therapy for hepatitis C virus infection?
GN Ioannou, JJ Feld - Gastroenterology, 2019 - Elsevier
Direct-acting antiviral (DAA) regimens are safe and effective at eradicating hepatitis C virus
(HCV) infection. Unfortunately, DAAs remain expensive, so treatment of all HCV-infected …
(HCV) infection. Unfortunately, DAAs remain expensive, so treatment of all HCV-infected …
Memory B cells of mice and humans
F Weisel, M Shlomchik - Annual review of immunology, 2017 - annualreviews.org
We comprehensively review memory B cells (MBCs), covering the definition of MBCs and
their identities and subsets, how MBCs are generated, where they are localized, how they …
their identities and subsets, how MBCs are generated, where they are localized, how they …
Low CD21 expression defines a population of recent germinal center graduates primed for plasma cell differentiation
In this study, we report that antigen-specific CD19+ CD27+ CD21lo (CD21lo) B cells are
transiently induced 14 to 28 days after immunization, at the time germinal centers (GCs) …
transiently induced 14 to 28 days after immunization, at the time germinal centers (GCs) …
Atypical memory B cells in human chronic infectious diseases: An interim report
S Portugal, N Obeng-Adjei, S Moir, PD Crompton… - Cellular …, 2017 - Elsevier
Immunological memory is a remarkable phenomenon in which survival of an initial infection
by a pathogen leads to life-long protection from disease upon subsequent exposure to that …
by a pathogen leads to life-long protection from disease upon subsequent exposure to that …
Zeb2 drives the formation of CD11c+ atypical B cells to sustain germinal centers that control persistent infection
X Gao, Q Shen, JA Roco, B Dalton, K Frith… - Science …, 2024 - science.org
CD11c+ atypical B cells (ABCs) are an alternative memory B cell lineage associated with
immunization, infection, and autoimmunity. However, the factors that drive the transcriptional …
immunization, infection, and autoimmunity. However, the factors that drive the transcriptional …